Results 21 to 30 of about 1,172,761 (182)

Immunogenicity of transmissible gastroenteritis virus (TGEV) M gene delivered by attenuated Salmonella typhimurium in mice. [PDF]

Virus Genes, 2016
Attenuated Salmonella typhimurium (S. typhimurium) was selected as a transgenic vehicle for the development of live mucosal vaccines against transmissible gastroenteritis virus (TGEV) based on the M gene. An approximate 1.0 kb DNA fragment, encoding for glycoprotein M, was amplified by RT-PCR and cloned into eukaryotic expression vector pVAX1.
Qing Y, Liu J, Huang X, Li Y, Zhang Y, Chen J, Wen X, Cao S, Wen Y, Wu R, Yan Q, Ma X.   +11 more
europepmc   +4 more sources

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV. [PDF]

Viruses, 2019
Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus causing high morbidity and mortality in porcine herds worldwide. Although both inactivated and live attenuated vaccines have been extensively used, the emergence of highly virulent strains and the recurrent outbreaks even in vaccinated farms highlight the need of effective vaccines ...
Pascual-Iglesias A, Sanchez CM, Penzes Z, Sola I, Enjuanes L, Zuñiga S.   +5 more
europepmc   +6 more sources

Transmissible gastroenteritis virus (TGEV) infection alters the expression of cellular microRNA species that affect transcription of TGEV gene 7. [PDF]

Int J Biol Sci, 2015
Transmissible gastroenteritis virus (TGEV) is a member of Coronaviridae family. TGEV infection has emerged as a major cause of severe gastroenteritis and leads to alterations of many cellular processes. Meanwhile, the pathogenic mechanism of TGEV is still unclear.
Song X, Zhao X, Huang Y, Xiang H, Zhang W, Tong D.   +5 more
europepmc   +3 more sources

In vitro and in vivo evaluation of thapsigargin as an antiviral agent against transmissible gastroenteritis virus

Veterinary Research
Swine enteric coronaviruses (SeCoVs) pose a significant threat to the global pig industry, but no effective drugs are available for treatment. Previous research has demonstrated that thapsigargin (TG), an ER stress inducer, has broad-spectrum antiviral ...
Yang Li, Yuanyuan Liu, Yunhang Zhang, Chen Tan, Yifei Cai, Yue Zhang, Jianing Chen, Yuguang Fu, Guangliang Liu   +8 more
doaj   +2 more sources

Myricetin inhibits transmissible gastroenteritis virus replication by targeting papain-like protease deubiquitinating enzyme activity

Frontiers in Microbiology
Myricetin, a natural flavonoid found in various foods, was investigated for its antiviral effect against transmissible gastroenteritis virus (TGEV). This α-coronavirus causes significant economic losses in the global swine industry.
Jiahao Fan, Pengyuan Xi, Huimao Liu, Xu Song, Xinghong Zhao, Xun Zhou, Yuanfeng Zou, Yuping Fu, Lixia Li, Renyong Jia, Zhongqiong Yin   +10 more
doaj   +3 more sources

First report of transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) in pigs from Poland. [PDF]

BMC Vet Res
Porcine transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) are swine coronaviruses belonging to the genus Alphacoronavirus in the family Coronaviridae. To date, there are no reports on the prevalence and genetic characterization of these viruses in domestic pigs from Poland.
Antas M, Olech M.
europepmc   +4 more sources

All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Inflammation in IPEC-J2 Cells via Suppressing the RLRs/NF‐κB Signaling Pathway

Frontiers in Immunology, 2022
Transmissible gastroenteritis virus (TGEV) infection can cause transmissible gastroenteritis (TGE), especially in suckling piglets, resulting in a significant economic loss for the global pig industry.
Junning Pu, Daiwen Chen, Gang Tian, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Yuheng Luo, Hui Yan, Bing Yu   +11 more
doaj   +1 more source

The dna vaccine combining the adjuvant porcine il-12 with the spike gene of transmissible gastroenteritis virus enhances the immune response in swine [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018
Transmissible gastroenteritis (TGE), cause by transmissible gastroenteritis virus (TGEV), is an acute digestive and highly infectious disease in piglets. In this study, porcine interleukin-12 immunological adjuvant combined with a DNA vaccine bearing the
Xunliang LI, Pengchong LI, Huijie CHEN, Fandan MENG, Xiaofeng REN, Guangxing LI   +5 more
doaj   +1 more source

Transmissible Gastroenteritis Virus Infection Enhances SGLT1 and GLUT2 Expression to Increase Glucose Uptake. [PDF]

PLoS ONE, 2016
Transmissible gastroenteritis virus (TGEV) is a coronavirus that causes villus atrophy, followed by crypt hyperplasia, reduces the activities of intestinal digestive enzymes, and disrupts the absorption of intestinal nutrients.
Lei Dai, Wei Wei Hu, Lu Xia, Mi Xia, Qian Yang   +4 more
doaj   +1 more source

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes [PDF]

, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Enjuanes, L., Plana-Duran, J., Reimann, I., Moormann, R.J.M., Sola, I., Plana Duran, J., Alonso, S., Izeta, A., Teifke, J.P., Teifke, Jens Peter, Reimann, Ilona, Balasch, M.   +11 more
core   +1 more source