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Transmissible spongiform encephalopathies in ruminants
Veterinary Clinics of North America: Food Animal Practice, 2004Transmissible spongiform encephalopathies (TSEs) have been observed in North American sheep, cervidae, and cattle. The causative agent of TSEs seems to be proteins that induce a conformational change in normal host proteins. Common clinical signs ofTSEs include chronic weight loss and deteriorating neurologic function.
Jeff W, Tyler, John R, Middleton
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Animal Transmissible Spongiform Encephalopathies and Genetics
Veterinary Research Communications, 2003The genotype of the host plays a crucial role in the pathogenesis of transmissible spongiform encephalopathies (TSEs). In this respect, the most important factor is represented by the gene of the prion protein (PrP). The present work summarizes the currently available knowledge on the genetic basis of TSEs focusing, in particular, on sheep scrapie ...
AGRIMI U. +11 more
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The Other Transmissible Spongiform Encephalopathies
Reviews in the Neurosciences, 2005Murine leukemia viruses may produce encephalopathies that have the same characteristics as those induced by infectious proteins or prions: neuronal loss, astrocytosis, and absence of inflammatory response. The pathogenic mechanism is still poorly understood but it seems that it involves the envelope proteins (Env), which may be misprocessed in the cell,
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Transmissible spongiform encephalopathies
2001Abstract Unique among the neurodegenerative diseases, the spongiform encephalopathies are transmissi- ble, either experimentally or as a result of cannibalistic, iatrogenic, or zoonotic infections in humans. First described in the 1920s by Creutzfeldt and Jakob, whose names memorialize its most common form, human spongiform ...
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Origin and timing of brain lesions in term infants with neonatal encephalopathy
Lancet, The, 2003Frances Cowan +2 more
exaly

