Results 51 to 60 of about 29,448 (249)

Successful transplantation of bovine testicular cells to heterologous recipients [PDF]

Reproduction, 2006
While heterologous germ cell transplantation was successful in pigs and goats, autologous transplantation alone has been reported to result in donor-derived spermatogenesis in cattle. The objective of this study was to investigate whether the transplantation of heterologous germ cells could result in colonization of recipient testes in cattle of ...
Jonathan R. Hill, Ina Dobrinski, Rhonda Davey, Muren Herrid, Soma Vignarajan   +4 more
openaire   +2 more sources

In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators

British Journal of Pharmacology, EarlyView.
Background and Purpose Cystic fibrosis (CF) is due to loss‐of‐function variants of the CF transmembrane conductance regulator (CFTR) channel. The most effective treatment for people with CF carrying the F508del mutation is the triple combination of elexacaftor–tezacaftor–ivacaftor (ETI).
Emanuela Pesce, Valeria Tomati, Valeria Capurro, Mariateresa Lena, Cristina Pastorino, Miro Astore, Serdar Kuyucak, Benoit Chevalier, Elvira Sondo, Federico Cresta, Alice Dighero, Vito Terlizzi, Cristina Fevola, Stefano Costa, Maria Cristina Lucanto, Valeria Daccò, Laura Claut, Francesca Ficili, Benedetta Fabrizzi, Renata Bocciardi, Federico Zara, Carlo Castellani, Luis J. V. Galietta, Shafagh A. Waters, Alexandre Hinzpeter, Nicoletta Pedemonte   +25 more
wiley   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi, Francesca Gigola, Reto M. Baertschiger, Marco Del Riccio, Hanna Garnier, Gloria Gonzalez, York Tien Lee, Amos Loh, Luca Pio, Sophie Branchereau   +9 more
wiley   +1 more source

Influence of Clinical and Psychosocial Factors on the Acceptance of no Human Organs in Transplants: Xenotransplants

Brazilian Journal of Transplantation, 2022
Introduction: Xenotransplantation is defined as the transplantation of cells, organs and tissues between different species. It is studied as an alternative method to acquire an adequate supply of human organs, which imbalance in demand results in ...
Cinthia Laureano Pavan, Moacir Fernandes de Godoy, Eliane Tiemi Miyazaki, Rita de Cassia Martins Alves da Silva, Caio Hussid de Goes, Lilian Castiglioni, Renato Ferreira da Silva   +6 more
doaj  

Development of α 1,3-galactosyltransferase Inactivated and Human Membrane Cofactor Protein Expressing Homozygous Transgenic Pigs for Xenotransplantation

Journal of Animal Reproduction and Biotechnology, 2017
Transplantation is considered to be a very useful approach to improve human welfare and to prolong life-span. Heterologous organ transplantation using pig organs which are similar to human beings and easy to make mass-production has known as one of the ...
Gunsup Lee, Sang Hyoun Park, Haesun Lee, Soo-Jeong Ji, Joo Yung Lee, Sung-June Byun, Seongsoo Hwang, Kyung Woon Kim, Sun A Ock, Keon Bong Oh   +9 more
doaj   +1 more source

Impact and Effectiveness of COVID-19 mRNA Vaccination Against COVID-19 Hospitalisation in Paediatrics: A Cohort Study Using Two Linked Data Sources in Spain. [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Purpose Despite Spain's > 2 million COVID‐19 paediatric cases before 2024, few required hospitalisations (8900). We aimed to estimate the effectiveness of two‐dose COVID‐19 vaccinations against hospitalisation ‘with’ and ‘for’ COVID‐19 in paediatrics.
Castillo-Cano B, Riefolo F, Villalobos F, Martín-Pérez M, Messina D, Elbers R, Brink-Kwakkel D, Bissacco CA, Segundo E, Saiz LC, Leache L, Barbieri E, Vaz T, Gini R, Klungel O, Martín-Merino E.   +15 more
europepmc   +2 more sources

HETEROLOGOUS TRANSPLANTATION OF MAMMALIAN TUMORS [PDF]

Journal of Experimental Medicine, 1941
The successful heterologous transplantation of several human tumors, including a breast carcinoma, a carcinoma of the colon, a melanotic sarcoma, and a fibrosarcoma, has been reported. Histologically, the appearance of the transplants of the carcinomata differed from that of the spontaneous tumors, but the directly observed growth of the transplanted ...
openaire   +5 more sources

Neocortical neurogenesis: a proneural gene perspective

The FEBS Journal, EarlyView.
The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan, Alexandra Moffat, Pierre Mattar, Carol Schuurmans   +3 more
wiley   +1 more source

Chicken Testicular Stem Cells

The Journal of Poultry Science, 2012
Transplantation of male germ cells into sterilized recipients in chicken opened a new approach for chicken transgenesis as well as for preservation of endangered bird species.
Pavel Trefil, Jitka Mucksová, Jiri Kalina   +2 more
doaj   +1 more source

Activation of immune signals during organ transplantation

Signal Transduction and Targeted Therapy, 2023
The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to clarify the immune signals, which are critical to the initiation ...
Qingwen Li, Peixiang Lan
doaj   +1 more source