Results 201 to 210 of about 5,669 (241)

PP374 Topic: AS13–Hematology/Oncology/Stem Cell Transplant/Immunology: PAEDIATRIC INTENSIVE CARE ADMISSIONS POST-HAEMATOPOIETIC STEM CELL TRANSPLANT: WHAT CAN WE LEARN?

Elisabeth Day, Christo Tsilifis, Edward W. Badger, Su Han Lum, G. Shenton, M Slatter, A Gennery, Rachel Agbeko   +7 more
openalex   +1 more source

PP-062 Role of the cellular immunology function test in preventing and treating the fungal infection following liver transplantation

, 2010
Huayu Yin, Rong Li, Jinle Ma, Z.-X. Wang, Zhang Fu   +4 more
openalex   +1 more source

Demonstration of Major Therapeutic Advantage From a Review of EU Conditional Marketing Authorizations in Oncology and Hematology

Clinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 1098-1105, April 2025.
In the EU, conditional marketing authorization is a pragmatic tool for early approval of a medicine that fulfills an unmet medical need. In the pharmaceutical legislation, an unmet medical need means that a condition lacks a satisfactory method for diagnosis, prevention, or treatment.
Florian Lasch, Joana R. B. Carvalho, Caroline Pothet   +2 more
wiley   +1 more source

PP114 Topic: AS13–Hematology/Oncology/Stem Cell Transplant/Immunology: MORTALITY IN CHILDREN WITH HEMOPHAGOCYTIC LYMPHOHISTIOCTYOSIS IN LOW-, LOW-MIDDLE-AND UPPER MIDDLE-INCOME COUNTRIES: A SYSTEMATIC REVIEW AND META-ANALYSIS

Melissa Hines, E. Trentham, Kevin Ryan, Carrie Price, Bettina Ehrlich, Michelle L. Hermiston, Asya Agulnik   +6 more
openalex   +1 more source

Japan's Conditional/Time‐Limited Early Approval System in Regenerative Medicine: A Case Study of Rise and Falls of Autologous Skeletal Myoblast Sheets

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1171-1174, May 2025.
Japan's conditional/time‐limited early approval program, initiated in 2014, aimed to advance regenerative medicine by expediting market access. However, the withdrawal of autologous skeletal myoblast sheets (Heartsheet) due to ineffectiveness raises concerns about the balance between rapid approval and scientific integrity.
Hayase Hakariya, Akihiko Ozaki, Yudai Kaneda, Tetsuya Tanimoto   +3 more
wiley   +1 more source

A Half-Century of Heterotopic Heart Transplantation in Mice: The Spearhead of Immunology Research

Decheng Yin, Oliver Dewald, Xiangyu Peng, Wei Nie, Song Rong, Diana Dudziak, Christian H.K. Lehmann, André Hoerning, Jian Fu   +8 more
openalex   +1 more source

Advancing Principled Pharmacoepidemiologic Research to Support Regulatory and Healthcare Decision Making: The Era of Real‐World Evidence

Clinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 927-937, April 2025.
A compilation of factors over the past decade—including the availability of increasingly large and rich healthcare datasets, advanced technologies to extract unstructured information from health records and digital sources, advancement of principled study design and analytic methods to emulate clinical trials, and frameworks to support transparent ...
Rohini K. Hernandez, Cathy W. Critchlow, Nancy Dreyer, Timothy L. Lash, Robert F. Reynolds, Henrik T. Sørensen, Jeff L. Lange, Nicolle M. Gatto, Rachel E. Sobel, Edward Chia‐Cheng Lai, Marieke Schoonen, Jeffrey S. Brown, Jennifer B. Christian, M. Alan Brookhart, Brian D. Bradbury   +14 more
wiley   +1 more source

Editorial: Immunology of allogeneic hematopoietic stem cell transplantation

Carmelo Gurnari, Rémy Duléry, Raffaella Greco, Sara Piccinelli   +3 more
openalex   +1 more source

Model‐Based Prediction of Clinically Relevant Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1413-1426, May 2025.
Platelet reconstitution after allogeneic hematopoietic cell transplantation (allo‐HCT) is heterogeneous and influenced by various patient‐ and transplantation‐related factors, associated with poor prognoses for poor graft function (PGF) and isolated thrombocytopenia.
Katharina M. Götz, Amin T. Turki, Katharina Och, Dominik Selzer, Christian Brossette, Norbert Graf, Jochen Rauch, Stefan Theobald, Yvonne Braun, Kerstin Rohm, Gabriele Weiler, Simeon Rüdesheim, Matthias Schwab, Lisa Eisenberg, Nico Pfeifer, Stephan Kiefer, Ulf Schwarz, Claudia Riede, Sigrun Smola, Dietrich W. Beelen, Dominic Kaddu‐Mulindwa, Jürgen Rissland, Jörg Bittenbring, Thorsten Lehr   +23 more
wiley   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Yasuharu Onishi, Yasunaru Sakuma, Yukiyo Wada, Akio Fujimura, Koichi Mizuta   +11 more
wiley   +1 more source