Results 41 to 50 of about 2,033 (187)

Late transplantation period of mice fetal intestine grafts: Morphometric aspects

open access: yes, 2007
Morphometric evaluation of the fetal intestinal graft in the late post-transplant period was done by using C57BL/6 mice. Under anesthesia, after hysterotomy, a transversal laparotomy was done in the fetus to harvest all intestines.
Ricardo Artigiani   +9 more
core   +1 more source

Synergistic Effect of Hyperglycemia and p27kip1 Suppression on Adult Mouse Islet Beta Cell Replication

open access: yesInternational Journal of Endocrinology, Volume 2012, Issue 1, 2012., 2012
The complementary role of hyperglycemia and p27kip1 suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27kip1 gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, p27kip1 protein content in cultured targeting islets was 22% of that in ...
Szu-Tah Chen   +5 more
wiley   +1 more source

High Yield of Rodent Islets with Intraductal Collagenase and Stationary Digestion—A Comparison with Standard Technique

open access: yesCell Transplantation, 1996
Intraductal distention of the pancreas with collagenase followed by stationary warm incubation improves the recovery of islets of Langerhans in the rat, but controlled studies are needed for valid comparison with standard isolation methods.
A.M. James Shapiro   +3 more
doaj   +1 more source

Inhibitory effect of injection of Corynebacterium parvum on the growth of tumour transplants in isogenic hosts. [PDF]

open access: yesBritish Journal of Cancer, 1966
Inhibitory effect of injection of Corynebacterium parvum on the growth of tumour transplants in isogenic hosts.
Woodruff, M F, Boak, J L
openaire   +2 more sources

Osteogenic Small Molecule FK506 for Enhanced Bone Formation in a Rabbit Ankle Fusion Model

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 10, Page 1805-1812, October 2025.
ABSTRACT Non‐union remains a significant complication following ankle fusion procedures, underscoring the need for effective osteogenic adjuvants to improve boney healing and fusion outcomes. This study investigates the osteogenic potential of FK506 (Tacrolimus), both in vitro and in vivo, for enhanced ankle fusion.
Nicholas Huffman   +6 more
wiley   +1 more source

Foetal pancreas transplantation in the rat

open access: yes, 1980
The efficacy of transplantation of foetal pancreas for correction of streptozotocin diabetes in the rat was studied using 17-18 day gestation foetal rat pancreata implanted under the renal capsule of the recipients.
Garvey, J. F. W.
core   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

A novel variant in the FLCN gene in a Chinese family with Birt–Hogg–Dubé syndrome

open access: yesMolecular Genetics &Genomic Medicine, Volume 12, Issue 7, July 2024.
In a BHD‐associated renal tumors Chinese family. A novel heterozygous variant (NM_144997.5:c.977dup) was identified in exon 9 of the FLCN gene, which broadens the spectrum of FLCN variants. We recommend that molecular analysis of the FLCN gene be performed in patients with suspected BHDS and their families.
He Miao   +6 more
wiley   +1 more source

Allogeneic anorectal transplantation in rats: technical considerations and preliminary results

open access: yesScientific Reports, 2016
Fecal incontinence is a challenging condition with numerous available treatment modalities. Success rates vary across these modalities, and permanent colostomy is often indicated when they fail.
F. Galvão   +10 more
semanticscholar   +1 more source

Abstract Book: 25th Congress of the European Hematology Association Virtual Edition, 2020

open access: yes, 2020
HemaSphere, Volume 4, Issue S1, Page 1-1168, June 2020.
wiley   +1 more source

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