Results 21 to 30 of about 2,033 (187)

miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.

Cardiovascular Research, 2016
Aims Cardiac transplantation is the only curative therapy for end-stage heart failure. Fibrosis is one of the major causes for impaired function of cardiac allografts.
Shashi K. Gupta, R. Itagaki, Xiang Zheng, S. Batkai, Sabrina Thum, Fareed Ahmad, L. V. Van Aelst, Amit Sharma, Maria-Teresa Piccoli, F. Weinberger, J. Fiedler, M. Heuser, S. Heymans, C. Falk, R. Förster, S. Schrepfer, T. Thum   +16 more
semanticscholar   +2 more sources

Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal–epidermal engineered skin substitutes

Pigment Cell and Melanoma Research, 2017
Steven T Boyce, Viki B Swope, Zalfa A Abdel-Malek   +2 more
exaly   +2 more sources

COMPLEMENT ACTIVATION AS A CAUSE FOR PRIMARY GRAFT FAILURE IN AN ISOGENEIC RAT MODEL OF HYPOTHERMIC LUNG PRESERVATION AND TRANSPLANTATION

Transplantation, 1997
Henry C Marsh, S M Scesney, Mehmet C Oz
exaly   +2 more sources

Hydrogen-Enriched Preservation Protects the Isogeneic Intestinal Graft and Amends Recipient Gastric Function During Transplantation

Transplantation, 2011
B. Buchholz, K. Masutani, T. Kawamura, Ximei Peng, Y. Toyoda, T. Billiar, A. Bauer, A. Nakao   +7 more
semanticscholar   +2 more sources

Whole‐Genome Sequencing Revealed a Late‐Maturing Isogenic Rice Koshihikari Integrated with Hd16 Gene Derived from an Ise Shrine Mutant

International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
We identified the key genes controlling the late maturation of the Japonica cultivar Isehikari, which was found at Ise Jingu Shrine and matures 6 days later than Koshihikari. We conducted a genetics‐based approach through this study. First, the latest mature plants, which flowered later than Isehikari, were segregated in the F2 and F3 generations of ...
Motonori Tomita, Ryotaro Tokuyama, Shosuke Matsumoto, Kazuo Ishii, Vijay Gahlaut   +4 more
wiley   +1 more source

A Comprehensive Update of Cerebral Organoids between Applications and Challenges

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
The basic technology of stem cells has been developed and created organoids, which have established a strong interest in regenerative medicine. Different cell types have been used to generate cerebral organoids, which include interneurons and oligodendrocytes (OLs). OLs are fundamental for brain development.
Xiaodong Li, Abdullah Shopit, Jingmin Wang, Sandra Moreno   +3 more
wiley   +1 more source

Inhibition of nuclear factor κB by IκB superrepressor gene transfer ameliorates ischemia-reperfusion injury after experimental lung transplantation

, 2005
ObjectivesIschemia-reperfusion injury after lung transplantation is associated with significant morbidity and mortality. The activation of the transcription factor nuclear factor κB is central to the 2 important pathways that characterize ischemia ...
T. Ishiyama, S. Dharmarajan, M. Hayama, H. Moriya, K. Grapperhaus, G. Patterson   +5 more
semanticscholar   +2 more sources

Cuff Anastomosis of Both Renal Artery and Vein to Minimize Thrombosis: A Novel Method of Kidney Transplantation in Mice

Journal of Investigative Surgery, 2022
Objectives Anastomosis of renal artery and renal vein in mouse models of kidney transplantation is technically challenging. Conventional technique using suture may result in vascular thrombosis.
Yi Yu, Jun Li, Zirong Bi, Chenglin Wu, Shicong Yang, Qifeng Jiang, Ronghai Deng, Qian Fu, Longshan Liu, Changxi Wang   +9 more
doaj   +1 more source

Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse

Cells, 2020
Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi, Sarah K. Wegner, Gabriele Spohn, Nina Müller, Sabine Harenkamp, Albrecht Stenzinger, Thalia Papayannopoulou, Halvard Bonig   +7 more
doaj   +1 more source

Intrauterine Transplantation of Isogenic Pancreatic Islets in Experimental Diabetic Rats.

Journal of Veterinary Medical Science, 1994
The effect of intrauterine transplantation (IU group) as a potential immunologically privileged site on the diabetic state of the recipient was compared with that of conventional intraperitoneal transplantation (IP group) using Fisher 344 rats. Islets were isolated from the pancreata of normal rats and transplanted into the uterus and peritoneal cavity
SAKONJU, Iwao, TAURA, Yasuho, NAKAICHI, Munekazu, NAKAMA, Sanenori, KAGABU, Satoshi   +4 more
openaire   +3 more sources