Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging [PDF]
ObjectiveEndomyocardial biopsy is the gold standard method for the diagnosis of cardiac allograft rejection. However, it causes damage to the heart.
Cheng Yang +14 more
core +4 more sources
Storage and allogeneic transplantation of peripheral nerve using a green tea polyphenol solution in a canine model [PDF]
Background In our previous study, allogeneic-transplanted peripheral nerve segments preserved for one month in a polyphenol solution at 4°C could regenerate nerves in rodents demonstrated the same extent of nerve regeneration as isogeneic fresh nerve ...
Ken Nakayama +9 more
core +4 more sources
Inhibition of mouse and rat lymphoproliferation by gangliosides [PDF]
Our previous study have demonstrated that Glycosphingolipids (GSLs) have an immunosuppressive effect on murine lymphoproliferation and IL-2 production.
Barbiéri, Clara Lúcia +4 more
core +4 more sources
Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Delayed Wound Healing in Diabetic Rats [PDF]
In this paper, we established a delayed wound healing model on diabetic rat to mimic the pathophysiology of clinical patients who suffered from diabetic foot ulcers.
Cai, Qian +4 more
core +2 more sources
Two Compartment Evaluation of Liver Grafts During Acellular Room Temperature Machine Perfusion (acRTMP) in a Rat Liver Transplant Model [PDF]
BackgroundSubnormothermic machine perfusion (SNMP) of liver grafts is currently less clinically developed than normothermic and hypothermic approaches, but may have logistical advantages.
Nader Abraham +18 more
doaj +2 more sources
Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse [PDF]
Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi +7 more
doaj +2 more sources
Immunosuppressive protocols with tacrolimus after cryopreserved aortal allotransplantation in rats. [PDF]
OBJECTIVES AND DESIGN:The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus ...
Rudolf Spunda +10 more
doaj +2 more sources
The role of HIF-1α-VEGF pathway in bronchiolitis obliterans after lung transplantation [PDF]
Background Graft function may be affected if the organ is exposed to hypoxia. We hypothesized that bronchiolitis obliterans (BO) after lung transplantation is associated with hypoxia-inducible factor-1α (HIF-1α). This study compares the expression of HIF-
Haichao Xu +6 more
doaj +2 more sources
Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply [PDF]
Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and ...
Azarov, Dimitri +21 more
core +15 more sources
Background Composite tissue allotransplants are performed for various defects when local, or distant reconstructive options are limited. Though this type of transplant replaces similar tissue, it is complicated by immunosuppression.
Cemile Nurdan Ozturk +4 more
doaj +1 more source

