Results 1 to 10 of about 1,074 (138)
Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging [PDF]
Frontiers in Immunology, 2023 ObjectiveEndomyocardial biopsy is the gold standard method for the diagnosis of cardiac allograft rejection. However, it causes damage to the heart.
Yunjie Jin +14 more
doaj +2 more sources
Role of Hyperglycemia in Isogeneic Islet Transplantation: An Experimental Animal Study [PDF]
Experimental and Clinical Endocrinology and Diabetes, 2008 Study the role of hyperglycemia-induced beta cell loss on grafted islet destruction.Male inbred rats were made diabetic by streptozotocin administration and used as islet donors and/or isograft recipients to probe directly the role of hyperglycemia as an important determinant of transplanted islet fate, following exclusion of immune-related causes of ...
Maria Satra
exaly +3 more sources
Journal of Diabetes Research, 2013 In this paper, we established a delayed wound healing model on diabetic rat to mimic the pathophysiology of clinical patients who suffered from diabetic foot ulcers.
Jiangbo Wan +4 more
doaj +2 more sources
Nanotherapeutics in transplantation: How do we get to clinical implementation? [PDF]
Am J Transplant, 2022 Patients undergoing organ transplantation transition from one life‐altering issue (organ dysfunction) to a lifelong commitment—immunosuppression. Regimens of immunosuppressive agents (ISAs) come with significant side effects and comorbidities. Recently, the use of nanoparticles (NPs) as a solution to the problems associated with the long‐term and ...
Plumblee L +5 more
europepmc +2 more sources
Journal of Investigative Surgery, 2022 Objectives Anastomosis of renal artery and renal vein in mouse models of kidney transplantation is technically challenging. Conventional technique using suture may result in vascular thrombosis.
Longshan Liu, Changxi Wang, Yi Yu
exaly +2 more sources
Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse [PDF]
Cells, 2020 Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi +7 more
doaj +2 more sources
Immunosuppressive protocols with tacrolimus after cryopreserved aortal allotransplantation in rats. [PDF]
PLoS ONE, 2018 OBJECTIVES AND DESIGN:The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus ...
Rudolf Spunda +10 more
doaj +2 more sources
Molecular Medicine Reports, 2018 The present study investigated the effects of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in transplantation-associated arteriosclerosis by observing their expression in transplanted aortas in rats. Allogenic and isogenic abdominal aortic transplantations were performed and grafts were removed from the recipients
Si-Dong, Wei +5 more
exaly +4 more sources
Journal of Reconstructive Microsurgery Open, 2023 Background Composite tissue allotransplants are performed for various defects when local, or distant reconstructive options are limited. Though this type of transplant replaces similar tissue, it is complicated by immunosuppression.
Cemile Nurdan Ozturk +4 more
doaj +1 more source
International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022 We identified the key genes controlling the late maturation of the Japonica cultivar Isehikari, which was found at Ise Jingu Shrine and matures 6 days later than Koshihikari. We conducted a genetics‐based approach through this study. First, the latest mature plants, which flowered later than Isehikari, were segregated in the F2 and F3 generations of ...
Motonori Tomita +4 more
wiley +1 more source