Results 1 to 10 of about 552,532 (299)
Additive manufacturing (AM) technologies have revolutionized the manufacturing sector due to their benefits, such as design flexibility, ease of operation, and wide material selection.
Raghunath Bhaskar +2 more
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Previous use of a mechanistic static model to accurately quantify the increased rosuvastatin exposure due to drug–drug interaction (DDI) with coadministered atazanavir underpredicted the magnitude of area under the plasma concentration–time curve ratio ...
Robert Elsby +5 more
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Quantitative phase microscopy for non-invasive live cell population monitoring
We present here a label-free development based on preexisting Quantitative Phase Imaging (QPI) that allows non-invasive live monitoring of both individual cells and cell populations.
Sherazade Aknoun +7 more
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Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection
Glia modulate neuronal excitability and seizure sensitivity by maintaining potassium and water homeostasis. A salt inducible kinase 3 (SIK3)-regulated gene expression program controls the glial capacity to buffer K+ and water in Drosophila, however ...
Hailun Li +2 more
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Despite the fact that glucose is the main fuel of the brain, hyperglycemia at hospital admission is generally associated with a poor functional outcome in stroke patients.
Laurent Suissa +8 more
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Genome and Evolutionary Analysis of Nosema ceranae: A Microsporidian Parasite of Honey Bees
Microsporidia comprise a phylum of single cell, intracellular parasites and represent the earliest diverging branch in the fungal kingdom. The microsporidian parasite Nosema ceranae primarily infects honey bee gut epithelial cells, leading to impaired ...
Qiang Huang +10 more
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Nucleocytoplasmic Transport [PDF]
Active transport of proteins and RNAs between the nucleus and cytoplasm is a major process in eukaryotic cells. Recently, factors that recognize transport substrates and mediate nuclear import or export have been characterized, revealing interactions that target substrates to the nuclear pore complexes, through which translocation occurs. Translocation
Görlich, D., Mattaj, I.
openaire +3 more sources
Extracellular Production of Glutathione by Recombinant Escherichia coli K-12
The goal of this study was to produce a sufficient amount of glutathione in the fermentation medium without the addition of cysteine. This would simplify and reduce the cost of its purification.
Hideyuki Suzuki +2 more
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Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii
Apicomplexan parasites are responsible for devastating diseases, including malaria, toxoplasmosis, and cryptosporidiosis. Current treatments are limited by emerging resistance to, as well as the high cost and toxicity of existing drugs.
Joachim Kloehn +4 more
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Cancer cells are reliant on nutrients such as glutamine, which enter the cell via the alanine/serine/cysteine transporter 2 (ASCT2). Here, authors use crystallography to show which amino-acid residues in the substrate-binding site are responsible for ...
Amanda J Scopelliti +4 more
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