Results 11 to 20 of about 516,723 (293)

Investigating the Properties of ABS-Based Plastic Composites Manufactured by Composite Plastic Manufacturing

Journal of Manufacturing and Materials Processing, 2022
Additive manufacturing (AM) technologies have revolutionized the manufacturing sector due to their benefits, such as design flexibility, ease of operation, and wide material selection.
Raghunath Bhaskar, Javaid Butt, Hassan Shirvani   +2 more
doaj   +1 more source

Mechanistic in vitro studies indicate that the clinical drug–drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3

Pharmacology Research & Perspectives, 2023
Previous use of a mechanistic static model to accurately quantify the increased rosuvastatin exposure due to drug–drug interaction (DDI) with coadministered atazanavir underpredicted the magnitude of area under the plasma concentration–time curve ratio ...
Robert Elsby, Hannah Coghlan, Jacob Edgerton, David Hodgson, Samuel Outteridge, Hayley Atkinson   +5 more
doaj   +1 more source

Quantitative phase microscopy for non-invasive live cell population monitoring

Scientific Reports, 2021
We present here a label-free development based on preexisting Quantitative Phase Imaging (QPI) that allows non-invasive live monitoring of both individual cells and cell populations.
Sherazade Aknoun, Manuel Yonnet, Zied Djabari, Fanny Graslin, Mark Taylor, Thierry Pourcher, Benoit Wattellier, Philippe Pognonec   +7 more
doaj   +1 more source

Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome

Metabolites, 2020
Despite the fact that glucose is the main fuel of the brain, hyperglycemia at hospital admission is generally associated with a poor functional outcome in stroke patients.
Laurent Suissa, Jean-Marie Guigonis, Fanny Graslin, Emilie Doche, Ophélie Osman, Yves Chau, Jacques Sedat, Sabine Lindenthal, Thierry Pourcher   +8 more
doaj   +1 more source

Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection

eLife, 2021
Glia modulate neuronal excitability and seizure sensitivity by maintaining potassium and water homeostasis. A salt inducible kinase 3 (SIK3)-regulated gene expression program controls the glial capacity to buffer K+ and water in Drosophila, however ...
Hailun Li, Lorenzo Lones, Aaron DiAntonio   +2 more
doaj   +1 more source

Glucose Transport and Transporters in the Endomembranes [PDF]

International Journal of Molecular Sciences, 2019
Glucose is a basic nutrient in most of the creatures; its transport through biological membranes is an absolute requirement of life. This role is fulfilled by glucose transporters, mediating the transport of glucose by facilitated diffusion or by secondary active transport.
Beáta Lizák, András Szarka, Yejin Kim, Kyu-sung Choi, Csilla E. Németh, Paola Marcolongo, Angelo Benedetti, Gábor Bánhegyi, Éva Margittai   +8 more
openaire   +5 more sources

Genome and Evolutionary Analysis of Nosema ceranae: A Microsporidian Parasite of Honey Bees

Frontiers in Microbiology, 2021
Microsporidia comprise a phylum of single cell, intracellular parasites and represent the earliest diverging branch in the fungal kingdom. The microsporidian parasite Nosema ceranae primarily infects honey bee gut epithelial cells, leading to impaired ...
Qiang Huang, Qiang Huang, Zhi Hao Wu, Zhi Hao Wu, Wen Feng Li, Rui Guo, Jin Shan Xu, Xiao Qun Dang, Zheng Gang Ma, Yan Ping Chen, Jay D. Evans   +10 more
doaj   +1 more source

Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. [PDF]

, 2016
ObjectivesThiamin deficiency is highly prevalent in patients with sepsis, but the mechanism by which sepsis induces thiamin deficiency is unknown. This study aimed to determine the influence of various severity of sepsis on carrier-mediated intestinal ...
Fang, Liwei, Said, Hamid M, Sassoon, Catherine S, Subramanian, Veedamali S, Zhu, Ercheng   +4 more
core   +2 more sources

The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism

mBio, 2022
The Staphylococcus aureus cidABC and lrgAB operons encode members of a well-conserved family of proteins thought to be involved in programmed cell death (PCD).
Jennifer L. Endres, Sujata S. Chaudhari, Xinyan Zhang, Janani Prahlad, Shu-Qi Wang, Lily A. Foley, Sorin Luca, Jeffrey L. Bose, Vinai C. Thomas, Kenneth W. Bayles   +9 more
doaj   +1 more source

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter. [PDF]

, 1994
We report that activators and inhibitors of protein kinase C (PKC) and protein phosphatases regulate the activity of a cloned rat brain gamma- aminobutyric acid (GABA) transporter (GAT1) expressed in Xenopus oocytes.
Janis L. Corey, Norman Davidson, Henry A. Lester, Nicholas C. Brecha, Michael W. Quick   +4 more
openalex   +3 more sources