Results 21 to 30 of about 77,105 (268)

Regulation of mariner transposition: the peculiar case of Mos1. [PDF]

PLoS ONE, 2012
BACKGROUND: Mariner elements represent the most successful family of autonomous DNA transposons, being present in various plant and animal genomes, including humans.
Jérôme Jaillet, Murielle Genty, Jeanne Cambefort, Jacques-Deric Rouault, Corinne Augé-Gouillou   +4 more
doaj   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
AGI, Arabidopsis Genome Initiative, Alix, Alix, Alix, Bandelt, Bateman, Bennetzen, Brunner, Casacuberta, Cui, Darling, DeMarco, Deragon, Edgar, Eichler, Fedoroff, Feschotte, Gaeta, Gish, Grandbastien, Hawkins, He, Heslop-Harrison, IHGSC, Inaba, Inagaki, Itoh, Jacobs, Jiang, Johnston, Kapitonov, Kapitonov, Kawasaki, Kazazian, Kubis, Kubis, Kuhn, Kurtz, Le, Leflon, Lenoir, Lysak, Maddison, Meyers, Miura, Morgante, Morgante, Nacken, Nicolas, Ozeki, O’Neill, Pereira, Peterson, Posada, Rocarro, Rodríguez, Schwarzacher, Shiba, Snowden, Snowdon, Sonnhammer, Strachan, Suzuki, Swofford, Talbert, Town, Turcotte, U, Vicient, Walbot, Wang, Wendel, Wicker, Wicker, Yang, Yang, Yu, Zabala, Zabala, Zhang, Zhang   +80 more
core   +1 more source

Prevalence of Antibiotic Resistome in Ready-to-Eat Salad [PDF]

, 2020
Ready-to-eat salad harbors microorganisms that may carry various antibiotic resistance genes (ARGs). However, few studies have focused on the prevalence of ARGs on salad, thus underestimating the risk of ARGs transferring from salad to consumers. In this
Giles, Madeline, Neilson, Roy, Wei, Meng-Yun, Yang, Xiao-Ru, Zhang, Qi, Zheng, Fei, Zhou, Shu-Yi-Dan, Zhu, Yong-Guan   +7 more
core   +2 more sources

Epigenetic Application of ATAC-Seq Based on Tn5 Transposase Purification Technology

Genetics Research, 2022
Background. Assays of transposase accessible chromatin sequencing (ATAC-seq) is an efficient assay to investigate chromatin accessibility, which depends on the activity of a robust Tn5 transposase to fragment the genome while cutting in the sequencing ...
Wangchun Li, U Tim Wu, Yu Cheng, Yanhao Huang, Lipeng Mao, Menghan Sun, Congling Qiu, Lin Zhou, Lijuan Gao   +8 more
doaj   +1 more source

A Broad Range of Dose Optima Achieve High-level, Long-term Gene Expression After Hydrodynamic Delivery of Sleeping Beauty Transposons Using Hyperactive SB100x Transposase

Molecular Therapy: Nucleic Acids, 2016
The Sleeping Beauty (SB) transposon system has been shown to enable long-term gene expression by integrating new sequences into host cell chromosomes. We found that the recently reported SB100x hyperactive transposase conferred a surprisingly high level ...
Kelly M Podetz-Pedersen, Erik R Olson, Nikunj V Somia, Stephen J Russell, R Scott McIvor   +4 more
doaj   +1 more source

The folding of the specific DNA recognition subdomain of the sleeping beauty transposase is temperature-dependent and is required for its binding to the transposon DNA. [PDF]

PLoS ONE, 2014
The reaction of DNA transposition begins when the transposase enzyme binds to the transposon DNA. Sleeping Beauty is a member of the mariner family of DNA transposons.
Gage O Leighton, Tatiana A Konnova, Bulat Idiyatullin, Sophia H Hurr, Yuriy F Zuev, Irina V Nesmelova   +5 more
doaj   +1 more source

DDE transposases: Structural similarity and diversity [PDF]

Advanced Drug Delivery Reviews, 2010
DNA transposons are mobile DNA elements that can move from one DNA molecule to another and thereby deliver genetic information into human chromosomes in order to confer a new function or replace a defective gene. This process requires a transposase enzyme. During transposition DD[E/D]-transposases undergo a series of conformational changes.
Irina V, Nesmelova, Perry B, Hackett
openaire   +2 more sources

Transposition of Insertion Sequences was Triggered by Oxidative Stress in Radiation-Resistant Bacterium Deinococcus geothermalis

Microorganisms, 2019
During an oxidative stress-response assay on a putative Dps-like gene-disrupted Δdgeo_0257 mutant strain of radiation-resistant bacterium Deinococcus geothermalis, a non-pigmented colony was observed among the normal reddish color colonies. This non-
Chanjae Lee, Nakjun Choi, Min K. Bae, Kyungsil Choo, Sung-Jae Lee   +4 more
doaj   +1 more source

Structural insight into Tn3 family transposition mechanism

Nature Communications, 2022
Here the structure of transposase from Tn3 family is reported in apo form and bound to the transposon ends. The activation of the transposase induces metamorphic refolding of the catalytic domain suggesting the family-specific regulation mechanism.
Alexander V. Shkumatov, Nicolas Aryanpour, Cédric A. Oger, Gérôme Goossens, Bernard F. Hallet, Rouslan G. Efremov   +5 more
doaj   +1 more source

A comparative study of Tam3 and Ac transposition in transgenic tobacco and petunia plants [PDF]

, 1989
Transposition of the Anthirrinum majus Tam3 element and the Zea mays Ac element has been monitored in petunia and tobacco plants. Plant vectors were constructed with the transposable elements cloned into the leader sequence of a marker gene ...
A Day, A Herrmann, A Hoekema, A Hudson, AH Shirsat, B Baker, B Baker, C Martin, C Martin, C O'Reilly, Caius M. T. Rommens, D Inzé, DC Baulcombe, F Sanger, G Ditta, H Sommer, H. John J. Nijkamp, J Gielen, J Paz-Ares, Jacques Hille, JDG Jones, JI Yoder, Jie Gao, JM Goddard, KC Cone, LO Vodkin, M Motto, M-A Grandbastien, MA Sluys Van, Michel A. Haring, NV Fedoroff, P Maliga, P Nevers, P Vlaming De, R Carpenter, RA Jefferson, S Knapp, SL Dellaporta, T Maniatis, Tjeerd Volbeda, U Behrens, WD Sutton   +41 more
core   +4 more sources