Results 81 to 90 of about 68,477 (364)
Molecular Therapy: Nucleic AcidsThe Sleeping Beauty (SB) transposon system is a useful tool for genetic applications, including gene therapy. We discovered a hyperactive variant of the SB100X transposase, called SB200X.
Matthias Thomas Ochmann +5 more
doaj +1 more source
Transposase-assisted target-site integration for efficient plant genome engineering
NatureThe current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers genome-editing approaches to develop improved crops1,2.
Peng Liu +14 more
semanticscholar +1 more source
Increasing transposase abundance with ocean depth correlates with a particle-associated lifestyle
mSystemsTransposases are mobile genetic elements that move within and between genomes, promoting genomic plasticity in microorganisms. In marine microbial communities, the abundance of transposases increases with depth, but the reasons behind this trend remain ...
Juntao Zhong +5 more
doaj +1 more source
Recurrent co-domestication of PIF/Harbinger transposable element proteins in insects
Mobile DNA, 2022 Background Transposable elements (TEs) are selfish DNA sequences capable of moving and amplifying at the expense of host cells. Despite this, an increasing number of studies have revealed that TE proteins are important contributors to the emergence of ...
Dragomira N. Markova +4 more
doaj +1 more source
Image2_Insertion Specificity of the hATx-6 Transposase of Hydra magnipapillata.TIF
, 2021 Transposable elements (TE) are mobile genetic elements, present in all domains of life. They commonly encode a single transposase enzyme, that performs the excision and reintegration reactions, and these enzymes have been used in mutagenesis and creation
Laurence Ettwiller (15718) +5 more
core +1 more source
Transposase-mediated gene modulation in the placenta [PDF]
Placenta, 2017 The placenta is an organ vital to fetal development as well as the maintenance of a healthy pregnancy and plays a crucial role in developmental programming of the fetus. The mechanisms that link intrauterine milieu, fetal health and disease development later in life are poorly understood. Placenta-specific gene modulation, both by generating transgenic
Marlee Elston, Johann Urschitz
openaire +2 more sources
Table1_Insertion Specificity of the hATx-6 Transposase of Hydra magnipapillata.DOCX
, 2021 Transposable elements (TE) are mobile genetic elements, present in all domains of life. They commonly encode a single transposase enzyme, that performs the excision and reintegration reactions, and these enzymes have been used in mutagenesis and creation
Laurence Ettwiller (15718) +5 more
core +1 more source
Cell, 2018 Summary Conjugative transposition drives the emergence of multidrug resistance in diverse bacterial pathogens, yet the mechanisms are poorly characterized.
A. Rubio-Cosials +9 more
semanticscholar +1 more source
Table2_Insertion Specificity of the hATx-6 Transposase of Hydra magnipapillata.DOCX
, 2021 Transposable elements (TE) are mobile genetic elements, present in all domains of life. They commonly encode a single transposase enzyme, that performs the excision and reintegration reactions, and these enzymes have been used in mutagenesis and creation
Laurence Ettwiller (15718) +5 more
core +1 more source
An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. [PDF]
PLoS Genetics, 2008 Cockayne syndrome (CS) is a devastating progeria most often caused by mutations in the CSB gene encoding a SWI/SNF family chromatin remodeling protein. Although all CSB mutations that cause CS are recessive, the complete absence of CSB protein does not ...
John C Newman +4 more
doaj +1 more source