Results 171 to 180 of about 16,112 (276)
Evolution Landscape of PiggyBac (PB) Transposon in Beetles (Coleoptera). [PDF]
Wang Q +6 more
europepmc +1 more source
Multi‐Targeting Non‐Specific Genome Engineering in Bacteria
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun +7 more
wiley +1 more source
Deciphering the dynamics of active autonomous terminal inverted repeat transposons in the plant kingdom. [PDF]
Huang Z +4 more
europepmc +1 more source
Abstract INTRODUCTION Alzheimer's disease (AD) is a heterogeneous disease with diverse disease progression trajectories and brain pathology. Identifying AD subtypes is essential for understanding AD etiology, heterogeneity, and developing precise treatment. METHODS We applied a subspace‐merging algorithm to integrate multi‐omics data from brain tissues
Ziyan Song +5 more
wiley +1 more source
Possible Horizontal Gene Transfer of Novel Transposable Elements in <i>Anisakis simplex</i> between Hosts and Parasites. [PDF]
Hoshino N, Kuroda H.
europepmc +1 more source
Abstract Objectives The anti‐PD‐L1 antibody avelumab has demonstrated efficacy across multiple cancer types. Avelumab primarily blocks the PD‐1/L1 immune checkpoint, while inducing antibody‐dependent cellular cytotoxicity (ADCC) from CD16a+ NK cells.
Lachlan J Dobson +6 more
wiley +1 more source
In vivo CAR therapies: Turning the patient into their own CAR factory
Abstract Over the past decade, ex vivo autologous chimeric antigen receptor (CAR)‐T‐cell therapies have reshaped the treatment of B‐cell malignancies. Despite their remarkable clinical efficacy, their application remains limited by complex manufacturing processes, demanding logistics, long turnaround times, and substantial costs. In vivo CAR approaches
François Vilcot +3 more
wiley +1 more source
Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation. [PDF]
Rosspopoff O, Trono D, Feschotte C.
europepmc +1 more source
The diversification of PHIS transposon superfamily in eukaryotes [PDF]
Chu-Lin Xiong +5 more
core +1 more source
Antimicrobial stressors, that is, bile or mitomycin C, induce enlarged, nucleic acid‐rich bacterial extracellular vesicles in Vibrio cholerae that facilitate horizontal gene transfer in vitro and during intestinal colonisation. The findings provide a detailed comparison of control versus stress‐induced vesicles, identify bile as a host factor shaping ...
Dominik Fleischhacker +6 more
wiley +1 more source

