Results 191 to 200 of about 17,057 (320)

Deciphering the dynamics of active autonomous terminal inverted repeat transposons in the plant kingdom. [PDF]

aBIOTECH
Huang Z, Shi B, Huang L, Lisch D, Zhang X.   +4 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

The diversification of PHIS transposon superfamily in eukaryotes [PDF]

, 2015
Chu-Lin Xiong, Hong-Bo Zhang, Hua-Hao Zhang, Meng-Qiang Zhang, Min-Jin Han, Ze Zhang   +5 more
core   +1 more source

Possible Horizontal Gene Transfer of Novel Transposable Elements in <i>Anisakis simplex</i> between Hosts and Parasites. [PDF]

MicroPubl Biol
Hoshino N, Kuroda H.
europepmc   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation. [PDF]

Curr Opin Genet Dev
Rosspopoff O, Trono D, Feschotte C.
europepmc   +1 more source

Mutational Analysis of the Mu Transposase [PDF]

Journal of Biological Chemistry, 1998
Elena Krementsova, Michael J. Giffin, David Pincus, Tania A. Baker   +3 more
openaire   +1 more source

Synergistic Antitumor Activity of HAT Inhibitor A485 and XPO1 Inhibitor KPT8602 in Multiple Myeloma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Multiple myeloma (MM) remains the second most common hematologic malignancy, necessitating the identification of novel therapeutic targets. MM is characterized by a distinct epigenetic landscape driven by aberrant chromatin activation and super‐enhancer addiction.
Hong Xu, Wenqi Wu, Yanan Jiang, Jinhuan Wang, Yixin Zhai, Zhigang Zhao   +5 more
wiley   +1 more source

Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria. [PDF]

Genome Biol Evol
Martinez-Gutierrez CA, Huang Y, Bobay LM.   +2 more
europepmc   +1 more source