Results 211 to 220 of about 11,351 (298)

Predicted Functional Potentials of Bacterial Communities in Fermented Maize Products From Ghana, Nigeria, and Benin via 16S rRNA Amplicon Sequencing and PICRUSt2

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Publicly available 16S rRNA data from West African fermented maize products were analyzed in QIIME2, profiled with SILVA 138, and functionally predicted using PICRUSt2, revealing Lactobacillus‐dominated microbiomes driving key metabolic pathways in carbohydrate utilization, amino acid metabolism, DNA replication, and cell wall biosynthesis.
Humphrey P. K. Addy   +3 more
wiley   +1 more source

Emerging Dissemination of blaCTX‐M‐65 in Bovine E. coli in Spain Associated With IncHI2 Plasmids

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The resistome in ESBL/AmpC‐producing E. coli in livestock was diverse and dominated by plasmid‐borne genes Detection of host‐independent dissemination of AMR determinants mediated by shared plasmid types First report in Spanish cattle of blaCTX‐M‐65 on IncHI2 plasmids, an under‐reported ESBL in Europe Identification of potentially zoonotic clones in ...
Medelin Ocejo   +2 more
wiley   +1 more source

A versatile CRISPR-associated transposases-mediated toolkit for transcriptional regulation library. [PDF]

open access: yesNucleic Acids Res
Zhang Y   +9 more
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

open access: yesMedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li   +6 more
wiley   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge   +9 more
wiley   +1 more source

Microbial diversity of plant pathogens and insect endosymbionts in Reptalus artemisiae. [PDF]

open access: yesBMC Microbiol
Duduk B   +4 more
europepmc   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang   +7 more
wiley   +1 more source

How RAG1/2 evolved from ancestral transposases to initiate V(D)J recombination without transposition. [PDF]

open access: yesProc Natl Acad Sci U S A
Chen X   +12 more
europepmc   +1 more source

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