Results 221 to 230 of about 11,351 (298)

CHD4 Orchestrates Chromatin Remodeling to Activate the c‐Myc Signaling Pathway in Cancer Pathogenesis

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
CHD4 plays an essential role as an epigenetic regulator in the pathogenesis of multiple myeloma. The chromatin remodeling protein initially resolves G‐quadruplex (G4) secondary structures within the c‐Myc promoter region, thereby enhancing chromatin accessibility and promoting transcriptional activation.
Pinggang Ding   +10 more
wiley   +1 more source

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

open access: yesNeuroprotection, Volume 4, Issue 2, Page 131-142, June 2026.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei   +3 more
wiley   +1 more source

Are Putative Beta-Lactamases Posing a Potential Future Threat? [PDF]

open access: yesAntibiotics (Basel)
Mlynarcik P, Zdarska V, Kolar M.
europepmc   +1 more source

Pan‐NLRome analysis uncovers genetic diversity and evolutionary dynamics among rice, maize and sorghum

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Nucleotide‐binding leucine‐rich repeat (NLR) genes constitute one of the largest families of plant immune receptors and are central to crop disease resistance. Rice (Oryza sativa L.), maize (Zea mays L.), and sorghum (Sorghum bicolor (L.) Moench) are major crops underpinning global food security, and enhancing their immunity is critical for ...
Yanbo Wang   +14 more
wiley   +1 more source

Genomic and proteomic analyses of the maize root isolate <i>Rhodococcus erythropolis</i> NI86/21 reveal extensive genome plasticity and parallel evolution of herbicide degradation. [PDF]

open access: yesAppl Environ Microbiol
Kosztik J   +10 more
europepmc   +1 more source

Application of deep learning in crop research: From genomics to phenomics

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Deep learning, as a pivotal branch of machine learning, has demonstrated remarkable potential in advancing crop science by effectively integrating genomics and phenomics. This review systematically outlines the application of diverse deep learning architectures—such as convolutional neural networks, recurrent neural networks, and transformers ...
Zefeng Wu   +9 more
wiley   +1 more source

Elucidating the Functional and Taxonomic Diversity of Soil Microbial Communities From Three Commercial Soybean Farms in South Africa

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Prior to inoculation of soybeans, South African soils contain no Bradyhizobia that nodulate and fix nitrogen in soybeans. Soybean cultivation with prolonged inoculation resulted in the establishment and dominance of Bradyrhizobia in three soybean farms in South Africa as revealed by a microbial community study using shotgun metagenomics. ABSTRACT Prior
Khumbudzo Ndhlovu   +5 more
wiley   +1 more source

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller   +6 more
wiley   +1 more source

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