Results 181 to 190 of about 17,057 (320)

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, EarlyView.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

Investigating the Trans Effects of IS<italic>1</italic> Transposases on Intragenomic DNA Movements in <italic>Escherichia coli</italic>. [PDF]

Microb Physiol
Ord JW, Zhang Z, Wu J, Smith S, Feng Z, Ancheta K, Garrido LF, Yao G, Gupta S, Lee ET, Saier MH.   +10 more
europepmc   +1 more source

Chemical Exposures, DNA Methylation and Whole Blood DNA Damage in Pet Golden Retrievers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine multicentric lymphoma (CL) is a common and typically fatal cancer among dogs. Although certain breeds have a higher incidence of CL, its environmental risk factors remain uncertain. Exposures to herbicides and volatile organic compounds (VOCs) associate with non‐Hodgkin lymphoma in people.
Ashleigh N. Tindle, Mark E. Berres, Lauren Baker, Zhuonan Wu, Brenna Swafford, Julia Labadie, Lauren A. Trepanier   +6 more
wiley   +1 more source

scMOG: A graph neural network method for regulatory relationship‐preserving single‐cell multi‐omics integration

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Single‐cell multi‐omics sequencing technology provides a powerful tool for studying cellular heterogeneity. However, beyond the challenges of sparsity, heterogeneity, and dimensionality differences, a critical challenge in multi‐omics data integration lies in preserving the true regulatory relationships among molecular features.
Yucheng Lu, Xun Zhang, Hongwei Li
wiley   +1 more source

West Siberian Soil Resistome: Mobile Antibiotic Resistance in Agricultural Microbiomes. [PDF]

Antibiotics (Basel)
Skotareva AE, Sokolova EA, Voronina EN.
europepmc   +1 more source

Physiological impact of transposable elements encoding DDE transposases in the environmental adaptation of Streptococcus agalactiae.

Microbiology, 2014
Maud Fléchard, P. Gilot
semanticscholar   +1 more source

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

American Journal of Hematology, Volume 101, Issue 7, Page 1632-1649, July 2026.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan, Yang Liu, Heng‐Huan Lee, Wei Wang, Joseph McIntosh, Yijing Li, Jovanny Vargas, Yue Fei, Sairah Ahmed, Lukas M. Simon, Michael Wang   +10 more
wiley   +1 more source

Evolution Landscape of PiggyBac (PB) Transposon in Beetles (Coleoptera). [PDF]

Genes (Basel)
Wang Q, Shi S, Wang B, Chen X, Yang N, Gao B, Song C.   +6 more
europepmc   +1 more source

The Periodontal Pathogen Porphyromonas gingivalis Induces Expression of Transposases and Cell Death of Streptococcus mitis in a Biofilm Model

Infection and Immunity, 2014
A. Duran-Pinedo, V. Baker, Jorge Frias-Lopez   +2 more
semanticscholar   +1 more source

Non‐triazine photosystem II inhibitors provide effective control of metabolic atrazine‐resistant Amaranthus tuberculatus

Pest Management Science, Volume 82, Issue 7, Page 6864-6876, July 2026.
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez, Ryan S Henry, Kip E Jacobs, Damilola A Raiyemo, Isabel S Werle, Patrick J Tranel   +5 more
wiley   +1 more source