Results 101 to 110 of about 111,214 (295)
Mapping transposon insertion sites in a random selection of transposon insertion mutants.
, 2013 Mapping transposon insertion sites in a random selection of transposon insertion mutants.
Mary O’Connell Motherway (416753) +3 more
core +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Genetic profile of carbapenem-resistant Acinetobacter baumannii strains
Инфекция и иммунитетThe purpose of the research: the molecular genetic characteristic ofA. baumanniicarbapenem-resistant strains, including clonal affiliation, resistome and virulome pattern analysis, description of genetic environment resistance determinants, comparative ...
Anna E. Alekseeva +2 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Induction and Enhancement of Bacteriocin Production (Review)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley +1 more source
A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon
Molecular Therapy: Nucleic Acids, 2012 Nonviral vector systems are used increasingly in gene targeting and gene transfer applications. The piggyBac transposon represents an alternative integrating vector for in vivo gene transfer. We hypothesized that this system could achieve persistent gene
Erin R Burnight +7 more
doaj +1 more source
Current Opinion in Plant Biology, 2018 The genomes of most plant species are dominated by transposable elements (TEs). Once considered as 'junk DNA', TEs are now known to have a major role in driving genome evolution. Over the last decade, it has become apparent that some stress conditions and other environmental stimuli can drive bursts of activity of certain TE families and consequently ...
Manu J Dubin +2 more
openaire +4 more sources
Transposon‐Based Cellular Reprogramming to Induced Pluripotency
, 2016 Induced pluripotent stem (iPS) cells are a seminal discovery in the field of stem cells. iPS cells can be employed as patient-specific pluripotent stem cells in disease modelling, drug screens and potentially for autologous cell therapy, without the ...
Kues, Wilfried August, Wilfried A Kues
core +1 more source
Cytoskeleton, EarlyView.ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source