Results 31 to 40 of about 149,269 (182)

Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. [PDF]

, 2018
Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a ...
Abu Amar Mohamed Al Mamun, Asis Das, Bo Hu, Chenggang Wu, Hui Wu, Hung Ton-That, Jianhua Gu, Ju Huck Lee, Marvin Whiteley, Melissa D’Amore, Truc Thanh Luong   +10 more
core   +2 more sources

Cotton transposon-related variome reveals roles of transposon-related variations in modern cotton cultivation

Journal of Advanced Research
Introduction: Transposon plays a vital role in cotton genome evolution, contributing to the expansion and divergence of genomes within the Gossypium genus. However, knowledge of transposon activity in modern cotton cultivation is limited.
Shang Liu, Hailiang Cheng, Youping Zhang, Man He, Dongyun Zuo, Qiaolian Wang, Limin Lv, Zhongxv Lin, Ji Liu, Guoli Song   +9 more
doaj   +1 more source

A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon

Molecular Therapy: Nucleic Acids, 2012
Nonviral vector systems are used increasingly in gene targeting and gene transfer applications. The piggyBac transposon represents an alternative integrating vector for in vivo gene transfer. We hypothesized that this system could achieve persistent gene
Erin R Burnight, Janice M Staber, Pavel Korsakov, Xianghong Li, Benjamin T Brett, Todd E Scheetz, Nancy L Craig, Paul B McCray, Jr   +7 more
doaj   +1 more source

Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]

, 2019
Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian, Chung, Micky, Churchill, Daphnie, Clymer, Cody, Han, Mira V., Jonaid, G. M., Navarro Leija, Omar, Quinton, Sophia, Ross, Austin, Sexton, Corinne E.   +9 more
core   +2 more sources

A comparative study of Tam3 and Ac transposition in transgenic tobacco and petunia plants [PDF]

, 1989
Transposition of the Anthirrinum majus Tam3 element and the Zea mays Ac element has been monitored in petunia and tobacco plants. Plant vectors were constructed with the transposable elements cloned into the leader sequence of a marker gene ...
A Day, A Herrmann, A Hoekema, A Hudson, AH Shirsat, B Baker, B Baker, C Martin, C Martin, C O'Reilly, Caius M. T. Rommens, D Inzé, DC Baulcombe, F Sanger, G Ditta, H Sommer, H. John J. Nijkamp, J Gielen, J Paz-Ares, Jacques Hille, JDG Jones, JI Yoder, Jie Gao, JM Goddard, KC Cone, LO Vodkin, M Motto, M-A Grandbastien, MA Sluys Van, Michel A. Haring, NV Fedoroff, P Maliga, P Nevers, P Vlaming De, R Carpenter, RA Jefferson, S Knapp, SL Dellaporta, T Maniatis, Tjeerd Volbeda, U Behrens, WD Sutton   +41 more
core   +4 more sources

Giant transposons promote strain heterogeneity in a major fungal pathogen

mBio
Fungal infections are difficult to prevent and treat in large part due to strain heterogeneity, which confounds diagnostic predictability. Yet, the genetic mechanisms driving strain-to-strain variation remain poorly understood.
Emile Gluck-Thaler, Adrian Forsythe, Charles Puerner, Cecilia Gutierrez-Perez, Jason E. Stajich, Daniel Croll, Robert A. Cramer, Aaron A. Vogan   +7 more
doaj   +1 more source

Survey of molecular determinants in Gram-positive cocci isolated from hospital settings in Argentina

Journal of Infection in Developing Countries, 2007
Background: In order to study the resistance mechanisms to aminoglycosides, tetracyclines and erythromycin, we investigated the genetic determinants on 85 Streptococcus spp., Staphylococcus spp., and Enterococcus spp. isolates collected from 46 hospitals
Paola E. Jeric, Agustina Azpiroz, H. Lopardo, D. Centrón   +3 more
doaj   +3 more sources

Mouse B2 SINE elements function as IFN-inducible enhancers

eLife, 2023
Regulatory networks underlying innate immunity continually face selective pressures to adapt to new and evolving pathogens. Transposable elements (TEs) can affect immune gene expression as a source of inducible regulatory elements, but the significance ...
Isabella Horton, Conor J Kelly, Adam Dziulko, David M Simpson, Edward B Chuong   +4 more
doaj   +1 more source

Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]

, 2013
UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J, Emmett, Warren, Goh, Shan, Hussain, Haitham, Mullany, Peter, Riley, Thomas V   +5 more
core   +3 more sources

Chromosome Mapping and Molecular Characterization of the Tc1/Mariner Element in Rineloricaria (Siluriformes: Loricariidae)

Brazilian Archives of Biology and Technology, 2018
The Tc1/Mariner sequence was isolated and mapped on chromosomes aiming to verify the association of this transposable element (TE) and chromosomal rearrangements in Rineloricaria.
Cleberson Cezario Primo, Larissa Glugoski, Marcelo Ricardo Vicari, Viviane Nogaroto   +3 more
doaj   +1 more source