Results 11 to 20 of about 184,414 (333)

Whats, hows and whys of programmed DNA elimination in Tetrahymena [PDF]

open access: yesOpen Biology, 2017
Programmed genome rearrangements in ciliates provide fascinating examples of flexible epigenetic genome regulations and important insights into the interaction between transposable elements (TEs) and host genomes.
Tomoko Noto, Kazufumi Mochizuki
doaj   +1 more source

A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing

open access: yesCell Reports, 2022
Summary In animal germlines, transposons are silenced at the transcriptional or post-transcriptional level to prevent deleterious expression. Ciliates employ a more direct approach by physically eliminating transposons from their soma, utilizing piRNAs ...
Chundi Wang   +5 more
semanticscholar   +1 more source

Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac and Tol2 for Genome Engineering

open access: yesInternational Journal of Molecular Sciences, 2021
Transposons are mobile genetic elements evolved to execute highly efficient integration of their genes into the genomes of their host cells. These natural DNA transfer vehicles have been harnessed as experimental tools for stably introducing a wide ...
Nicolás Sandoval-Villegas   +3 more
semanticscholar   +1 more source

Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation

open access: yesMolecules and Cells, 2021
Summary PIWI proteins and their guiding Piwi-interacting small RNAs (piRNAs) are crucial for fertility and transposon defense in the animal germline.
D. Gebert   +5 more
semanticscholar   +1 more source

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences

open access: yesFrontiers in Genetics, 2021
Recently, we proved that Sleeping Beauty (SB) transposon integrates into non-TA sites at a lower frequency. Here, we performed a further study on the non-TA integration of SB and showed that (1) SB can integrate into non-TA sites in HEK293T cells as well
Yiting Zhou   +4 more
doaj   +1 more source

Functional genomics with a comprehensive library of transposon mutants for the sulfate-reducing bacterium Desulfovibrio alaskensis G20. [PDF]

open access: yes, 2014
UnlabelledThe genomes of sulfate-reducing bacteria remain poorly characterized, largely due to a paucity of experimental data and genetic tools. To meet this challenge, we generated an archived library of 15,477 mapped transposon insertion mutants in the
Arkin, Adam P   +11 more
core   +5 more sources

Campylobacter jejuni genes Cj1492c and Cj1507c are involved in host cell adhesion and invasion [PDF]

open access: yes, 2020
Background Campylobacter jejuni (C. jejuni) has been assigned as an important food-borne pathogen for human health but many pathogenicity factors of C. jejuni and human host cell responses related to the infection have not yet been adequately clarified.
Alter, Thomas   +4 more
core   +1 more source

Host Dependent-Transposon for a Plasmid Found in Aeromonas salmonicida subsp. salmonicida That Bears a catB3 Gene for Chloramphenicol Resistance

open access: yesAntibiotics, 2023
Plasmids that carry antibiotic resistance genes occur frequently in Aeromonas salmonicida subsp. salmonicida, an aquatic pathogen with severe consequences in salmonid farming. Here, we describe a 67 kb plasmid found in the A.
Pierre-Étienne Marcoux   +8 more
doaj   +1 more source

Molecular Characteristics of Enterococcus faecalis and Enterococcus faecium from Bulk Tank Milk in Korea

open access: yesAnimals, 2021
Enterococci are considered to be environmental mastitis-causing pathogens that can easily spread antimicrobial resistance or virulence genes via horizontal transfer.
Sunghyun Yoon, Young Ju Lee
doaj   +1 more source

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