Advanced Science, Volume 13, Issue 14, 9 March 2026.This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng +7 more
wiley +1 more source
Transposon activity and nucleotide triplet instability: new perspectives on their potential interplay in brain disorders. [PDF]
Front NeurosciPepe G +3 more
europepmc +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu +8 more
wiley +1 more source
Hi-C untangles the temporal dynamics of the children's gut resistome and mobilome, highlighting the role of transposable elements. [PDF]
mBioCifuentes SG +3 more
europepmc +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, Volume 13, Issue 14, 9 March 2026.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Correction to 'Comprehensive profiling of activity and specificity of RNA-guided transposons reveals opportunities to engineer improved variants'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
Whole-genome analysis of multidrug-resistant <i>Kluyvera intermedia</i> strain L-40-1 isolated from a pig with respiratory disease. [PDF]
J Vet SciLi H +6 more
europepmc +1 more source
Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design
Advanced Science, Volume 13, Issue 14, 9 March 2026.Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao +4 more
wiley +1 more source
A chromosome-level genome assembly for the mulberry thrips Pseudodendrothrips mori (Thysanoptera: Thripidae). [PDF]
Sci DataGuan DL +6 more
europepmc +1 more source
Tau PET overlap index correlation with neuropathological findings
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.
Seokbeen Lim +27 more
wiley +1 more source