Mobile Genetic Elements as Central Drivers of Antimicrobial Resistance: Molecular Mechanisms, Evolutionary Ecology, One Health Implications and Control Strategies. [PDF]
Hossain H +11 more
europepmc +1 more source
ABSTRACT Background The role of histone lactylation in diabetes associated renal fibrosis remains poorly defined. In this study, we investigated the contribution of histone H4 lysine 12 lactylation (H4K12la) to abnormal glycolysis and renal fibrogenesis in diabetic kidney disease (DKD) and evaluated sodium butyrate (NaB) as a potential therapeutic ...
Ping He +10 more
wiley +1 more source
Genomic characterization of vancomycin-resistant <i>Enterococcus faecium</i> and van-carrying mobile genetic elements in a tertiary hospital in northeastern China. [PDF]
Yao H +16 more
europepmc +1 more source
The ZmRACK1–ZmCDPK7–ZmAPX1 module regulates plant antiviral immunity
In maize, ZmRACK1 acts as a scaffold protein that bridges the cyclin‐dependent kinase ZmCDPK7 and the ascorbate peroxidase ZmAPX1, promoting ZmAPX1 activity to mitigate MCMV infection. Upon viral infection, P31 obstructs formation of the ZmRACK1‐ZmCDPK7‐ZmAPX1 complex, inhibiting ZmCDPK7‐mediated ZmAPX1 activity and promoting reactive oxygen species ...
Yuyang Zhang +13 more
wiley +1 more source
Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol +5 more
wiley +1 more source
Genes and physiological strategies in bacterial antibiotic resistance. [PDF]
Nadeem MS +9 more
europepmc +1 more source
Pathological convergence of a bacterial plant pathogen is associated with the horizontal transfer of an effector-containing mobile element. [PDF]
Bull EM, Agarwal V, Dillon MM.
europepmc +1 more source
Host-transposon mutualism supports regeneration in planarians. [PDF]
Lee HL +3 more
europepmc +1 more source
Comparative Genomics Provide Insights Into Karyotype Evolution in Vespertilionid Bats (Vespertilionidae, Chiroptera). [PDF]
Lan L +10 more
europepmc +1 more source

