Results 211 to 220 of about 52,950 (251)

Advancing In Vivo Chimeric Antigen Receptor T‐Cell Engineering to Accelerate Clinical Translation

MedComm, Volume 7, Issue 10, October 2026.
In vivo CAR‐T cell generation directly engineers endogenous T cells using pre‐manufactured gene delivery vectors that target T cells and deliver CAR‐encoding genetic material. The resulting CAR‐T cells expand in vivo and mediate antigen‐specific cytotoxicity.
Zhenxin Bai, Ming Yi, Shengtao Hu, Dixuan Xue, Luxin Wei, Lifeng Zhang, Zhijun Dai   +6 more
wiley   +1 more source

Mobilization of <i>bla</i>_VIM genes via the Tn6292 transposon among carbapenem-resistant <i>Enterobacter cloacae</i> complex isolates from colonized patients in a Spanish hospital. [PDF]

Microbiol Spectr
Ríos E, Rodríguez-Avial I, López R, Martínez M, González F, Delgado-Iribarren A, Culebras E.   +6 more
europepmc   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, Volume 70, Issue 10, Page 493-503, October 2026.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source

The complete sequence of the silkworm W chromosome uncovers its rapid evolution by large-scale duplications/deletions and translocation of W-linked genes. [PDF]

G3 (Bethesda)
Li W, Abe H, Chen Y, Liu J, Wang Y, Ajimura M, Li S, Xiao Y, Guo H, Wu J, Xu Y, Yang X, Yang X, Hao S, He Q, Fujii T, Sahara K, Yoshido A, Takehana Y, Naruse K, Arunkumar KP, Goldsmith MR, Smagghe G, Marec F, Xia Q, Mita K.   +25 more
europepmc   +1 more source

Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Transposon mutagenesis in biofilter‐associated Pseudomonas resinovorans MOB‐513 identifies a c‐di‐GMP‐dependent regulatory network involving type IV pili, two‐component systems, and diguanylate cyclases that controls Mn(II) oxidation and biofilm formation, providing new insight into microbial manganese cycling and biofilter performance.
Ainelén Piazza, Lucia Parra, Marilina Gaffuri, Jacob G. Malone, Jorgelina Ottado, Natalia Gottig   +5 more
wiley   +1 more source

Comprehensive genomic insights into lineages, virulence, and antibiotic resistance profiles of Campylobacter jejuni entailing a global One Health scenario. [PDF]

Gut Pathog
Qumar S, Hamad M, AbuOdeh R, Khoder G, Ahmed N.   +4 more
europepmc   +1 more source

Low Levels of Amino Acid Auxotrophy Among Environmental Pseudomonas Isolates

Environmental Microbiology, Volume 28, Issue 10, October 2026.
We explored the frequency of auxotrophy among co‐isolated natural Pseudomonas spp. We used a combination of in vitro and in silico approaches to assess the frequency of auxotrophy in communities and to understand the association between habitat, phylogeny and the occurrence of specific amino acid metabolic pathways.
Simon Maréchal, Benjamin Heiniger, Shaohua Gu, Swagatika Dash, Christian H. Ahrens, Rolf Kümmerli   +5 more
wiley   +1 more source

Integrated Comparative Genomics and Population Genomics Reveal the Genomic and Epigenomic Basis of Barley (<i>Hordeum vulgare</i>) Evolution and Domestication. [PDF]

Plants (Basel)
Yue W, Cai K, Liu L, Li Y, Cai S, Wang J.   +5 more
europepmc   +1 more source

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source