Results 101 to 110 of about 61,872 (307)

Migration of Bisphenol A and Its Derivatives From Epoxy Coatings and Demand for BPA‐NI Products: Scientific Insights and Perspectives Leading to Regulation (EU) 2024/3190

Chemistry – An Asian Journal, EarlyView.
The newly enacted Commission Regulation (EU) 2024/3190 addresses health concerns by promoting the use of BPA‐Non‐Intent (BPA‐NI) materials, which are formulated to avoid intentional BPA‐related chemical use and minimize contamination. ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical used in the production of polycarbonate and epoxy ...
Takeru Kajiyama, Kohei Kanazaki, Gopinath Venkatraman, Puteri Shafinaz Abdul‐Rahman, Ayami Matsushima   +4 more
wiley   +1 more source

Mechanisms of Transthyretin Inhibition of IAPP Amyloid Formation

Biomolecules, 2021
Amyloid-formation by the islet amyloid polypeptide (IAPP), produced by the β-cells in the human pancreas, has been associated with the development of type II diabetes mellitus (T2DM).
Sanduni Wasana Jayaweera, Solmaz Surano, Nina Pettersson, Elvira Oskarsson, Lovisa Lettius, Anna L. Gharibyan, Intissar Anan, Anders Olofsson   +7 more
doaj   +1 more source

Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant [PDF]

, 2023
Xun Sun, James A. Ferguson, Benjamin I. Leach, Robyn L. Stanfield, H. Jane Dyson, Peter E. Wright   +5 more
openalex   +1 more source

Multifaceted Effects of a Multiple Nitric Oxide Photoreleaser and its Photoproducts on Amyloid‐β Aggregation

ChemBioChem, EarlyView.
A blue light‐activatable NO photodonor sequentially releases two NO molecules accompanied by two stable photoproducts, showing differentiated effects on the β‐amyloid aggregation. Aberrant aggregation of β‐amyloid (Aβ) peptides into insoluble fibrils is recognized as one of the hallmarks of Alzheimer's disease (AD).
Francesca Laneri, Cristina Parisi, Salvatore Sortino   +2 more
wiley   +1 more source

Neuropathic pain experience in symptomatic and presymptomatic subjects carrying a transthyretin gene mutation

Frontiers in Neurology, 2023
IntroductionPain is a common symptom of hereditary transthyretin amyloidosis (ATTRv), however, its occurrence in late-onset ATTRv has not been investigated thoroughly. Our aim was to describe the pain experience and its impact on quality of life (QoL) in
Stefano Tozza, Marco Luigetti, Marco Luigetti, Giovanni Antonini, Anna Mazzeo, Daniele Severi, Andrea Di Paolantonio, Andrea Di Paolantonio, Luca Leonardi, Massimo Russo, Angela Romano, Angela Romano, Francesca Forcina, Luca Gentile, Maria Nolano, Maria Nolano, Consalvo Mattia, Consalvo Mattia, Fiore Manganelli   +18 more
doaj   +1 more source

Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin [PDF]

, 2002
Transthyretin (TTR) is a 55 kDa protein responsible for the transport of thyroid hormones and retinol in human serum. Misfolded forms of the protein are implicated in the amyloid diseases familial amyloidotic polyneuropathy and senile systemic ...
Hamilton JA, Hamilton JA, Jacobson DR, Jarvis JA, Nilsson SF, Saraiva MJ, Schnolzer M, Terry CJ, Thylen C, Wojtczak A   +9 more
core   +1 more source

Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis.

Circulation: Heart Failure, 2019
Cardiomyopathy is a manifestation of transthyretin amyloidosis (ATTR), which is an underrecognized systemic disease whereby the transthyretin protein misfolds to form fibrils that deposit in various tissues and organs.
M. Maurer, S. Bokhari, T. Damy, S. Dorbala, B. Drachman, M. Fontana, M. Grogan, A. Kristen, I. Lousada, J. Nativi-Nicolau, Candida Cristina Quarta, C. Rapezzi, F. Ruberg, R. Witteles, G. Merlini   +14 more
semanticscholar   +1 more source

Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid

ChemistryEurope, EarlyView.
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai, Youhi Hwang, Hiroki Umeda, Taka Sawazaki, Ikumi Tomizawa, Maiko Ono, Makoto Higuchi, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Harunobu Mitsunuma, Motomu Kanai   +11 more
wiley   +1 more source

Prevalence and characteristics of transthyretin amyloid cardiomyopathy in hypertrophic cardiomyopathy

ESC Heart Failure
Aims Recognition of transthyretin amyloid cardiomyopathy is increasing due to advances in cardiac imaging and diagnostic strategies, but questions remain regarding disease frequency and characteristics.
Pablo Garcia‐Pavia, Thibaud Damy, Nicolas Piriou, Roberto Barriales‐Villa, Francesco Cappelli, Catherine Bahus, Carmen Munteanu, Denis Keohane, Pablo Mallaina, Perry Elliott, the TTRACK investigators   +10 more
doaj   +1 more source

Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition

Biochemistry Research International, 2017
Malnutrition is a major underlying condition for mortality in children under five years of age in developing countries, particularly in Ethiopia. The most important forms of malnutrition in Ethiopia are protein and energy deficiencies.
Behailu Tsegaye, Amha Mekasha, Solomon Genet   +2 more
doaj   +1 more source