Results 121 to 130 of about 61,872 (307)
Changes in Left Ventricular Ejection Fraction and Clinical Trajectories of Transthyretin Cardiac Amyloidosis with Systolic Dysfunction [PDF]
Joshua Saef +9 more
openalex +1 more source
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies +23 more
wiley +1 more source
Hormone affinity and fibril formation of piscine transthyretin: the role of the N-terminal [PDF]
Transthyretin (TTR) transports thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3) in the blood of vertebrates. TH-binding sites are highly conserved in vertebrate TTR however, piscine TTR has a longer N-terminus which is thought to ...
A. Elisabeth Sauer-Eriksson +74 more
core +3 more sources
A phenomap of TTR amyloidosis to aid diagnostic screening
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos +4 more
wiley +1 more source
Transthyretin is a promising prognostic marker of non-developing pregnancy in hypothyroidism
Non-developing pregnancy is one of the most important problems in the practice of an obstetrician-gynecologist. Transthyretin is a transplacental transport protein of T3, T4 and is expressed in cyto- and syncytiotrophoblast cells.
A. A. Orazmuradov +5 more
doaj +1 more source
Fish and amphibians as test organisms for evaluation of effects caused by chemicals [PDF]
A large number of chemicals can contaminate aquatic environments and therefore be exposed to fish and amphibians during their sensitive stages of development.
Carlsson, Gunnar
core
Corino de Andrade disease: mechanisms and impact on reproduction [PDF]
Familial amyloid polyneuropathy was first described by Corino de Andrade in 1952 in Northern Portugal. It is a fatal autosomal dominant neurodegenerative disorder characterized by a progression of neurologic symptoms, beginning early in the reproductive ...
Barros, A. +3 more
core +1 more source
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer +25 more
wiley +1 more source
The Role of Transthyretin in Oligodendrocyte Development [PDF]
Bandar Alshehri +4 more
openalex +1 more source
Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy
Supplemental Digital Content is available in the text. Background: In patients with transthyretin amyloid cardiomyopathy, tafamidis reduces all-cause mortality and cardiovascular hospitalizations and slows decline in quality of life compared with placebo.
Dhruv S. Kazi +10 more
semanticscholar +1 more source

