Results 121 to 130 of about 61,872 (307)

Changes in Left Ventricular Ejection Fraction and Clinical Trajectories of Transthyretin Cardiac Amyloidosis with Systolic Dysfunction [PDF]

open access: gold, 2023
Joshua Saef   +9 more
openalex   +1 more source

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies   +23 more
wiley   +1 more source

Hormone affinity and fibril formation of piscine transthyretin: the role of the N-terminal [PDF]

open access: yes, 2008
Transthyretin (TTR) transports thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3) in the blood of vertebrates. TH-binding sites are highly conserved in vertebrate TTR however, piscine TTR has a longer N-terminus which is thought to ...
A. Elisabeth Sauer-Eriksson   +74 more
core   +3 more sources

A phenomap of TTR amyloidosis to aid diagnostic screening

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos   +4 more
wiley   +1 more source

Transthyretin is a promising prognostic marker of non-developing pregnancy in hypothyroidism

open access: yesФундаментальная и клиническая медицина
Non-developing pregnancy is one of the most important problems in the practice of an obstetrician-gynecologist. Transthyretin is a transplacental transport protein of T3, T4 and is expressed in cyto- and syncytiotrophoblast cells.
A. A. Orazmuradov   +5 more
doaj   +1 more source

Fish and amphibians as test organisms for evaluation of effects caused by chemicals [PDF]

open access: yes, 2007
A large number of chemicals can contaminate aquatic environments and therefore be exposed to fish and amphibians during their sensitive stages of development.
Carlsson, Gunnar
core  

Corino de Andrade disease: mechanisms and impact on reproduction [PDF]

open access: yes, 2017
Familial amyloid polyneuropathy was first described by Corino de Andrade in 1952 in Northern Portugal. It is a fatal autosomal dominant neurodegenerative disorder characterized by a progression of neurologic symptoms, beginning early in the reproductive ...
Barros, A.   +3 more
core   +1 more source

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer   +25 more
wiley   +1 more source

The Role of Transthyretin in Oligodendrocyte Development [PDF]

open access: gold, 2020
Bandar Alshehri   +4 more
openalex   +1 more source

Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy

open access: yesCirculation, 2020
Supplemental Digital Content is available in the text. Background: In patients with transthyretin amyloid cardiomyopathy, tafamidis reduces all-cause mortality and cardiovascular hospitalizations and slows decline in quality of life compared with placebo.
Dhruv S. Kazi   +10 more
semanticscholar   +1 more source

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