Results 81 to 90 of about 29,341 (237)

Systemic transthyretin amyloidosis: carpal tunnel syndrome in a Portuguese population (CarPoS) [PDF]

Exploration of Cardiology
Carpal tunnel syndrome (CTS) is the most common type of entrapment neuropathy and affects approximately 1% to 5% of the general population, mostly patients older than 50 years.
Sofia Pimenta, Ana Martins, Miguel Carvalho, Bernardo Sousa Pinto, Adriana Sá Pinto, Janete Santos, Inês Fortuna, Pedro Madureira, Pedro Negrão, Jorge Pereira, Lúcia Costa, Elisabete Martins   +11 more
doaj   +1 more source

A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH [PDF]

, 2019
Mitsuharu Ueda, Masamitsu Okada, Mineyuki Mizuguchi, Barbara Kluve‐Beckerman, Kyosuke Kanenawa, Aito Isoguchi, Yohei Misumi, Masayoshi Tasaki, Mitsuharu Ueda, Akinori Kanai, Ryoko Sasaki, Teruaki Masuda, Yasuteru Inoue, Toshiya Nomura, Satoru Shinriki, Tsuyoshi Shuto, Hirofumi Kai, Taro Yamashita, Hirotaka Matsui, Merrill D. Benson, Yukio Ando   +20 more
openalex   +1 more source

Conjunctival lymphangiectasia and retinal angiopathy in hereditary transthyretin amyloidosis [PDF]

, 2022
Nikhil S. Patil, Munir M. Iqbal, Lulu Bursztyn   +2 more
openalex   +1 more source

Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis

Drug Design, Development and Therapy, 2019
Veena Mathew,1 Annabel K Wang1,2 1Department of Neurology, UCI ALS and Neuromuscular Center, University of California, Irvine, Orange, CA, USA; 2Neurology Section, Tibor Rubin VA Medical Center, Long Beach, CA, USA Abstract: Hereditary transthyretin ...
Mathew V, Wang AK
doaj  

Proteomic Analysis of Serum in Cardiac Transthyretin Amyloidosis: Diagnostic and Prognostic Implications for Biomarker Discovery

Biomedicines
Background/Objectives: Having serum biomarkers available for cardiac transthyretin amyloidosis (ATTR-CA) would be beneficial for diagnosis and prognosis. This study aimed to identify potential ATTR-CA biomarkers through proteomic analysis.
Joanna Waś, Monika Gawor-Prokopczyk, Agnieszka Sioma, Rafał Szewczyk, Aleksandra Pel, Jolanta Krzysztoń-Russjan, Magdalena Niedolistek, Dorota Sokołowska, Jacek Grzybowski, Łukasz Mazurkiewicz   +9 more
doaj   +1 more source

Structure of ATTRv-F64S fibrils isolated from skin tissue of a living patient

Nature Communications
Amyloid transthyretin-derived (ATTR) amyloidosis is a degenerative, systemic disease characterized by transthyretin fibril deposition in organs like the heart, kidneys, liver, and skin.
Jun Yu, Xuefeng Zhang, Sandra Pinton, Elena Vacchi, Andrea Cavalli, Matteo Pecoraro, Giorgia Melli, Andreas Boland   +7 more
doaj   +1 more source

The hydrophobic C‐terminal sequence of transthyretin affects its catalytic kinetics towards amidated neuropeptide Y

FEBS Open Bio, 2019
Transthyretin (TTR) is a transporter for thyroid hormone and retinol binding protein that has recently been reported to have proteolytic activity against certain substrates, including amidated neuropeptide Y (NPY).
Sukanya Tangthavewattana, Ladda Leelawatwattana, Porntip Prapunpoj   +2 more
doaj   +1 more source

Familial Amyloidotic Polyneuropathy with Leptomeningeal and Cardiac Involvement in a Patient with Gly73Glu Transthyretin Gene Mutation — Non-invasive Diagnostic Approach with Multimodality Imaging Findings: a Case Report [PDF]

, 2022
BCK Chow, SSM Lo, JCY Lee, JB Chiang, HF Chan, CB Ho, L. D. Szeto, KW Tang   +7 more
openalex   +1 more source

Hereditary transthyretin amyloidosis (ATTRv)

Current Problems in Cardiology
Hereditary transthyretin (TTR) amyloidosis (ATTRv amyloidosis) is a devastating disease characterized by broad range of clinical manifestations, including predominantly neurological, predominantly cardiac, and mixed phenotypes. This wide phenotypic variability hindered timely disease diagnosis and risk stratification in the past, especially in ...
Filippos Triposkiadis, Alexandros Briasoulis, Randall C. Starling, Dimitrios E. Magouliotis, Christos Kourek, George E Zakynthinos, Efstathios K. Iliodromitis, Ioannis Paraskevaidis, Andrew Xanthopoulos   +8 more
openaire   +3 more sources

Real-world outcomes in non-endemic hereditary transthyretin amyloidosis with polyneuropathy: a 20-year German single-referral centre experience [PDF]

, 2020
Matthias N. Ungerer, Ernst Hund, Jan Purrucker, Laura Huber, Christoph Kimmich, Fabian aus dem Siepen, Selina Hein, Arnt V. Kristen, Katrin Hinderhofer, Jennifer Kollmer, Stefan Schönland, Ute Hegenbart, Markus Weiler   +12 more
openalex   +1 more source