Results 71 to 80 of about 615,852 (293)

Cold molecular ions on a chip [PDF]

open access: yes, 2014
We report the sympathetic cooling and Coulomb crystallization of molecular ions above the surface of an ion-trap chip. N$_2^+$ and CaH$^+$ ions were confined in a surface-electrode radiofrequency ion trap and cooled by the interaction with laser-cooled ...
Mokhberi, A., Willitsch, S.
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Ménage-à-trois: The ratio of bicarbonate to CO2 and the pH regulate the capacity of neutrophils to form NETs

open access: yesFrontiers in Immunology, 2016
In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder   +14 more
doaj   +1 more source

Eccentricity Trap: Trapping of Resonantly Interacting Planets near the Disk Inner Edge

open access: yes, 2010
Using orbital integration and analytical arguments, we have found a new mechanism (an "eccentricity trap") to halt type I migration of planets near the inner edge of a protoplanetary disk.
Binney   +14 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Induction of trap formation in nematode-trapping fungi by a bacterium. [PDF]

open access: yesFEMS microbiology letters, 2011
Three soil bacterial strains were identified as Chryseobacterium sp. TFB on the basis of their 16S rRNA gene sequences. Conidia of Arthrobotrys oligospora produced a few mycelial traps (MT) and conidial traps (CT) when cultured with bacterial cells that they did not produce when cultured with a bacterial cell-free culture filtrate.
Lei, Li   +7 more
openaire   +3 more sources

Hysteresis effects in rotating Bose-Einstein condensates

open access: yes, 2006
We study the formation of vortices in a dilute Bose-Einstein condensate confined in a rotating anisotropic trap. We find that the number of vortices and angular momentum attained by the condensate depends upon the rotation history of the trap and on the ...
B. Jackson   +5 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Formation fluid characteristics and hydrocarbon accumulation in the Dongying sag, Shengli Oilfield

open access: yesPetroleum Exploration and Development, 2012
Based on the analysis of geochemical characteristics and distribution of different formation waters, a new origin identification standard was established for the formation water in the Paleogene Shahejie Formation in the Dongying Sag. The migration paths
Shanwen ZHANG   +8 more
doaj   +1 more source

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