Results 221 to 230 of about 1,229,293 (285)

Multi‐Organ Inflammatory and Endocrine Crosstalk Shapes the Early Brain Response to Combined Burn and Blast Injury

The FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Concomitant burn injury and blast‐induced mild TBI lead to a magnified neuroimmune response shaped by endocrine stress‐related pathways and IL‐1R1‐dependent inflammatory signals, which also produce cytokine‐mediated impairment of erythropoiesis. These integrated systemic and CNS responses illustrate how inflammation, hematopoietic adaptation, and early
Hana C. Schwierling, Satarupa Sengupta, John G. Noel, Christopher J. O'Connell, Andrew S. Potter, Mike Adam, Matthew J. Robson, Jason C. Gardner   +7 more
wiley   +1 more source

Predictive models for the occurrence of expansive intracranial hematomas and outcomes after surgical evacuation in patients with traumatic brain injury in Uganda: a prospective cohort study. [PDF]

Front Surg
Kamabu LK, Bbosa GS, Oboth R, John Baptist S, Kaddumukasa MN, Deng D, Lekuya HM, Kataka LM, Kiryabwire J, Galukande M, Sajatovic M, Kaddumukasa M, Fuller AT, Haglund MM.   +13 more
europepmc   +1 more source

The Boron–Neuron Connection: The Potential of Boron‐Containing Molecules for Treating Incurable Amyotrophic Lateral Sclerosis

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai, Billy Vuong, Muhammad Shaharyar K. Afridi, Sasha Leggett, Hemin Roghzai, Geoffrey K. Tranmer   +5 more
wiley   +1 more source

Pituitary adenylate cyclase-activating polypeptide and mitochondrial homeostasis in neuronal injury: mechanisms and translational prospects. [PDF]

Front Immunol
Sun W, Mo R, Zhai M.
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

GFAP Use in Emergency Medicine-A Narrative Review. [PDF]

NeuroSci
Ghazala MT, Sula I, Jihwaprani MC, Aljabri AH, Saif SY, Alhebshi A, Alatae HG, Hassan AE.   +7 more
europepmc   +1 more source

In a Patient With Pre‐Existing Tetraparesis, GBS Should Be Diagnosed Only if All Differential Causes Have Been Ruled Out

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT In a patient with pre‐existing proximal tetraparesis, progression to the distal limb muscles after 3 years should be attributed to Guillain‐Barre syndrome only if differential causes of tetraparesis were thoroughly ruled out.
Sounira Mehri, Josef Finsterer
wiley   +1 more source

Association between craniofacial trauma and traumatic brain injury in patients admitted to a tertiary care hospital: a prospective cross-sectional study. [PDF]

J Trauma Inj
Aziz PA, Wajid A, Ahmed E, Mehmood A, Qureshi BA, Khan H, Bhatti ZN.   +6 more
europepmc   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Fluid Biomarkers for the Antemortem Detection of Chronic Traumatic Encephalopathy: A Critical Review. [PDF]

Neurol Int
Shatirishvili N.
europepmc   +1 more source