Results 11 to 20 of about 75,341 (263)
The Group of Treatment Resistant Schizophrenias. Heterogeneity in Treatment Resistant Schizophrenia (TRS) [PDF]
Schizophrenia is composed of a heterogeneous group of patient segments. Our current notion of the heterogeneity in schizophrenia is based on patients presenting with diverse disease symptom phenotypes, risk factors, structural and functional ...
Bruce J. Kinon
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Pharmacotherapy for treatment-resistant schizophrenia
Meghan E Mcilwain1,2, Jeff Harrison1, Amanda J Wheeler1,3, Bruce R Russell1,21School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 2Centre for Brain Research, Faculty of Medical and Health Sciences ...
Meghan E Mcilwain +3 more
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Cariprazine: Patients with Treatment-Resistant Schizophrenia
Thomas Aubel Kliniken Essen-Mitte, Klinik für Psychiatrie, Psychotherapie, Psychosomatik und Suchtmedizin, Essen, GermanyCorrespondence: Thomas AubelKliniken Essen-Mitte, Klinik für Psychiatrie, Psychotherapie, Psychosomatik und Suchtmedizin ...
Aubel T
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Identifying treatment-resistant schizophrenia [PDF]
I was surprised to read the paper of Howes et al .[1][1] No control group was investigated. This paper implies that any patient for whom a third antipsychotic is considered ought to be considered for clozapine, and if they are not started on clozapine, this constitutes an unacceptable delay.
Kiriakos, Xenitidis +2 more
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Treatment resistance in schizophrenia [PDF]
Alternative drugs may offer clearer understanding of underlying mechanisms Since the 1950s, when chlorpromazine was introduced into psychiatric practice, antipsychotic drugs have been the cornerstone of the management of schizophrenia. They have three main functions: to treat the positive symptoms of acute schizophrenic episodes; to reduce ...
E C, Johnstone, R, Sandler
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Genetic association analysis of N-methyl-d-aspartate receptor subunit gene GRIN2B and clinical response to clozapine [PDF]
OBJECTIVE: Approximately 30% of patients with schizophrenia fail to respond to antipsychotic therapy and are classified as having treatment-resistant schizophrenia.
Abrams +144 more
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Antipsychotic medication for childhood-onset schizophrenia [PDF]
We review the development of several new approaches for extending the performance of Brillouin based slow light systems. In particular we describe the use of cavity effects to enhance the achievable delays, gain saturation to decouple the delay and ...
Datta, Soumitra +2 more
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Dissociative Model in Patients With Resistant Schizophrenia
BackgroundSchizophrenia is a severe mental illness in which, despite the growing number of antipsychotics from 30 to 50% of patients remain resistant to treatment. Many resistance factors have been identified.
Georgi Panov
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The influence of 5-HT(2C) and MDR1 genetic polymorphisms on antipsychotic-induced weight gain in female schizophrenic patients [PDF]
We investigated the relationships between functional genetic variants of the 5-HT(2C) receptor and multidrug-resistant protein (MDR1), coding for P-glycoprotein, and second generation antipsychotic (SDA)-induced weight gain among 108 female schizophrenic
Bilušić, Hrvoje +5 more
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The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain.
Amber N. Edinoff +7 more
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