Results 61 to 70 of about 3,088,273 (255)
Event-Tree Based Sequence Mining Using LSTM Deep-Learning Model
Complexity, 2021 During the operation of modern technical systems, the use of the LSTM model for the prediction of process variable values and system states is commonly widespread.
János Abonyi +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Accurate Reconstruction of Molecular Phylogenies for Proteins Using Codon and Amino Acid Unified Sequence Alignments (CAUSA) [PDF]
, 2011 Based on molecular clock hypothesis, and neutral theory of molecular evolution, molecular phylogenies have been widely used for inferring evolutionary history of organisms and individual genes.
Jingjie Hu +7 more
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
GNAT multiple sequence alignment and output files from IQ-TREE
Multiple sequence alignment and phylogenetic analysis of GNAT sequences from vertebrates.Alignment was created using ClustalO with standard settings. The phylogenetic tree was created using IQ-TREE (v. 1.6.12) using the following settings: -t BIONJ -nt 8
Treethinkers NIG (14572193) +2 more
core +1 more source
PHYRN: a robust method for phylogenetic analysis of highly divergent sequences.
PLoS ONE, 2012 Both multiple sequence alignment and phylogenetic analysis are problematic in the "twilight zone" of sequence similarity (≤ 25% amino acid identity). Herein we explore the accuracy of phylogenetic inference at extreme sequence divergence using a variety ...
Gaurav Bhardwaj +14 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
BEAST: Bayesian evolutionary analysis by sampling trees
BMC Evolutionary Biology, 2007 Background The evolutionary analysis of molecular sequence variation is a statistical enterprise. This is reflected in the increased use of probabilistic models for phylogenetic inference, multiple sequence alignment, and molecular population genetics ...
Drummond Alexei J, Rambaut Andrew
doaj +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Rooted Tree Sequence Problems [PDF]
application/pdf論文(Article)Let D be a directed tree. If deg⁻ (r)=O for some vertex r ED, and deg⁻ (v)=l for any vertex v ED with v ≠ r ,then r is called a root and D is called a rooted tree.
3325, TAKAHASHI, Masaya
core +1 more source