Results 61 to 70 of about 1,226,857 (290)
Bisection of trees and sequences
Discrete Mathematics, 1993 A bisectable graph \(G\) is the edge-disjoint union of two isomorphic subgraphs. The authors show a quantified version of the fact that any tree with \(e\) edges contains a bisectable subgraph with (asymptotically) almost all edges.
Alon, N., Caro, Y., Krasikov, I.
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FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Benchmarking tree and ancestral sequence inference for B cell receptor sequences [PDF]
Frontiers in Immunology, 2018 AbstractB cell receptor sequences evolve during affinity maturation according to a Darwinian process of mutation and selection. Phylogenetic tools are used extensively to reconstruct ancestral sequences and phylogenetic trees from affinity-matured sequences. In addition to using general-purpose phylogenetic methods, researchers have developed new tools
Davidsen, Kristian +1 more
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
BMC Research Notes, 2018 Objective The body of DNA sequence data lacking taxonomically informative sequence headers is rapidly growing in user and public databases (e.g. sequences lacking identification and contaminants).
Thomas Sauvage +3 more
doaj +1 more source
Fragmentary Gene Sequences Negatively Impact Gene Tree and Species Tree Reconstruction [PDF]
Molecular Biology and Evolution, 2017 Species tree reconstruction from genome-wide data is increasingly being attempted, in most cases using a two-step approach of first estimating individual gene trees and then summarizing them to obtain a species tree. The accuracy of this approach, which promises to account for gene tree discordance, depends on the quality of the inferred gene trees. At
Erfan, Sayyari +2 more
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
BMC Genomics, 2018 Background Several methods have been developed for the accurate reconstruction of gene trees. Some of them use reconciliation with a species tree to correct, a posteriori, errors in gene trees inferred from multiple sequence alignments. Unfortunately the
Emmanuel Noutahi, Nadia El-Mabrouk
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Event-Tree Based Sequence Mining Using LSTM Deep-Learning Model
Complexity, 2021 During the operation of modern technical systems, the use of the LSTM model for the prediction of process variable values and system states is commonly widespread.
János Abonyi +2 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Large enzyme families such as the groups of zinc-dependent alcohol dehydrogenases (ADHs), long chain alcohol oxidases (AOxs) or amine dehydrogenases (AmDHs) with, sometimes, more than one million sequences in the non-redundant protein database and ...
Fernanda L. Sirota +8 more
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