Results 191 to 200 of about 275,584 (397)

IMMU-07. Interim analysis of the HIT-HGG Rez Immunvac study - Dendritic cell vaccination with partial Treg depletion and double checkpoint blockade in children with relapsed high-grade gliomas. [PDF]

, 2022
Matthias Eyrich, Jürgen Krauß, Maryam Ghaffari, Ignazio Caruana, Johannes Rachor, Camelia‐Maria Monoranu, Brigitte Bison, Stefan Rückriegel, Matthias Wölfl, Elisabeth Miller, Paul‐Gerhardt Schlegel, Christof M. Kramm   +11 more
openalex   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

IL-2 promotes early Treg reconstitution after allogeneic hematopoietic cell transplantation [PDF]

, 2017
Brian C. Betts, Joseph Pidala, Jongphil Kim, Asmita Mishra, Taiga Nishihori, Lia Perez, José L. Ochoa-Bayona, Farhad Khimani, Kelly Walton, Ryan Bookout, Michael L. Nieder, Divis Khaira, Marco L. Davila, Melissa Alsina, Teresa Field, Ernesto Ayala, Frederick L. Locke, Marcie Riches, Mohamed A. Kharfan‐Dabaja, Hugo F. Fernández, Claudio Anasetti   +20 more
openalex   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source

Targeting immunosuppression by Tregs with monoclonal antibodies against GARP [PDF]

, 2016
Stéphanie Liénart, Julie Stockis, Olivier Dedobbeleer, Sophie Lucas   +3 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Mass Spectrometry analysis of glycolipids from resting and activated Tregs

, 2020
Gang Wu, Stuart M. Haslam, Anne Dell, Paul R. Crocker   +3 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Helminth Induced Immunoregulation and Novel Therapeutic Avenue of Allergy

Journal of Asthma and Allergy, 2020
Birhanu Ayelign,1 Yonas Akalu,2 Banchamlak Teferi,3 Meseret Derbew Molla,4 Tewodros Shibabaw4 1Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar ...
Ayelign B, Akalu Y, Teferi B, Molla MD, Shibabaw T   +4 more
doaj  

FRI0187 PRELIMINARY EXPLORATION OF NEW METHODS TREAT TO PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: REGULATING TH17/TREG CELL BALANCE BY RAPAMICIN AND ALL-TRANS RETINOIC ACID [PDF]

, 2019
Yanfang Chu, Chunmiao Zhao, Bingying Zhang, Xuxia Wang, Yiqi Wang, Jia An, Junwei Chen, Xiaofeng Li   +7 more
openalex   +1 more source