Recrutamento de células dendríticas imaturas e linfócitos T reguladores (Treg) em lesões associadas ao vírus Epstein-Barr (EBV): papel da citocina MIP3 [PDF]
Paulo Henrique Braz‐Silva
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Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
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Extracorporeal Photopheresis Enhances the Frequency and Function of Highly Suppressive FoxP3 + Treg Subsets in Heart Transplanted Individuals. [PDF]
Mottola M+16 more
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Tregs utilize β-galactoside-binding protein to transiently inhibit PI3K/p21ras activity of human CD8+ T cells to block their TCR-mediated ERK activity and proliferation [PDF]
Dolgor Baatar+5 more
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Designing next‐generation immune cell therapies with nanomaterials
Nanomaterials are transforming immune cellular therapies (ICT) by addressing challenges like tumor accessibility and lengthy manufacturing. This perspective highlights innovations such as magnetic nanoparticles for target identification, lipid nanoparticles for T cell stimulation, and nanoparticle‐mediated gene cytokine delivery. These advances promise
Kangfu Chen, Wenhan Wang, Zongjie Wang
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Exosomes from Tregs mitigate lung damage caused by smoking via inhibiting inflammation and altering T lymphocyte subsets in COPD rats. [PDF]
Tao X, Tian H, Wang G, Sun Y, Zhao L.
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Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi+11 more
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Single-cell RNA sequencing reveals an IL1R2+Treg subset driving immunosuppressive microenvironment in HNSCC. [PDF]
Guo H+5 more
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Association of Immune Cell Phenotypes With Oral Cancer: A Two-Sample Mendelian Randomisation Study. [PDF]
Yang Y, Xu J, Lu Y, Tang Z, He J.
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CD73 promotes the immunoregulatory functions of hepatic Tregs through enzymatic and nonenzymatic pathways in MASLD development. [PDF]
Jin H+12 more
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