Results 301 to 310 of about 275,584 (397)

Integrating machine learning and multi-omics analysis to explore Treg-associated programmed cell death features in clear cell renal cell carcinoma. [PDF]

Cancer Cell Int
Dai H, Zhang X, Yin L, Chen H, Liu K, Li J, Li H, Sheng L, Wu H, Wang J, He S, Li Q, Lv Y.   +12 more
europepmc   +1 more source

Micro‐Organ Chip Deciphers Tumor‐Derived G‐CSF as Remote Commander of Lung Pre‐Metastatic Niche via VEGFA‐KDR Cascade

Advanced Science, EarlyView.
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang, Xiaoying Huang, Lingchuan Ma, Zixing Chen, Tianyao Li, Lijian Wang, Yutong Guo, Hu Xu, Junqi Li, Jiang‐Jiang Qin, Xiang Wang, Yuhong Cao, Kai Miao   +12 more
wiley   +1 more source

Constitutively Active Stat5b Expression in Dendritic Cells Enhances Treg-Mediated Elimination of Autoreactive CD8⁺ T Cells in Autoimmune Diabetes. [PDF]

Int J Mol Sci
Khongorzul P, Khan FU, Levasseur D, Gris D, Amrani A.   +4 more
europepmc   +1 more source

TREG cell therapy [PDF]

Nature Reviews Rheumatology, 2010
openaire   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

MIF Regulates the Th17/Treg Ratio to Exacerbate Kidney Injury in Chronic Kidney Disease. [PDF]

Inflammation
Zhang R, Fan K, Wang H, Chen J, Lu C, Li L, Chang R, Qiao M, Zhang Y, Zhang H, Li Y, Zhang J, Ning Y, Dong H.   +13 more
europepmc   +1 more source

Muscular Treg cells [PDF]

Nature Medicine, 2014
openaire   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

<i>TBX21</i> correlates with an immunosuppressive tumor microenvironment and Treg/Th17 imbalance in prostate cancer. [PDF]

Front Oncol
Wang H, Liu Z, Xu X, Wang Q, Chang P, He L, Ouyang J.   +6 more
europepmc   +1 more source