Results 251 to 260 of about 4,874,341 (306)

Early Synovial Regulatory T Cell Engagement in Posttraumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early postinjury biologic processes within the synovium shape disease trajectories. We investigated whether synovial Treg cells are engaged during the early phase following joint injury and whether experimental enrichment of this ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

HBx/WDR5 enhances IGF-1 transcription in hepatocellular carcinoma cells and promotes recruitment, infiltration, and activity of Treg cells. [PDF]

Immunol Res
Wang E, Sun S, Li H, Jia Y, Bai Z.
europepmc   +1 more source

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber, Mario R. Angeli, Hashem Mohammadian, Hannah Labinsky, Maria Gabriella Raimondo, Richard Demmler, Yuko Ariza, Thomas Wohlfahrt, Markus Luber, Yi‐Nan Li, Jörg H.W. Distler, Tobias Bäuerle, Georg Schett, Simon Rauber, Andreas Ramming, Alina M. Ramming   +15 more
wiley   +1 more source

Mast Cells Promote Inflammatory Th17 Cells and Impair Treg Cells Through an IL-1β and PGE₂ Axis. [PDF]

J Inflamm Res
Leveque E, Joulia R, Battut L, Laurent C, Valitutti S, Cénac N, Dietrich G, Espinosa E.   +7 more
europepmc   +1 more source

Extraintestinal Reprogramming of Colon‐Derived CD4+ Intraepithelial Lymphocytes Reveals a Mechanism Underlying the Gut–Joint Axis

Arthritis &Rheumatology, EarlyView.
Objective The gut–joint axis is a central paradigm in spondyloarthritis, yet the cellular mechanisms linking intestinal and joint immunity remain poorly understood. One potential link is T cell receptor αβ+ CD4+ colon intraepithelial lymphocytes (cIELs) that can traffic to extraintestinal tissues, including the joint.
Sarah M. Danielson, Connor Eck, Sucai Liu, Anna Helena Jonsson, Kristine A. Kuhn   +4 more
wiley   +1 more source

Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice. [PDF]

JCI Insight
Hosking SL, Moldenhauer LM, Tran HM, Chan HY, Groome HM, Lovell EA, Green ES, O'Hara SE, Roberts CT, Foyle KL, Davidge ST, Robertson SA, Care AS.   +12 more
europepmc   +1 more source

Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells. [PDF]

Cell Mol Immunol
Sharma A, Sharma G, Gao Z, Li K, Li M, Wu M, Kim CJ, Chen Y, Gautam A, Choi HB, Kim J, Kwak JM, Lam SM, Shui G, Paul S, Feng Y, Kang K, Im SH, Rudra D.   +18 more
europepmc   +1 more source

Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity. [PDF]

BMC Med
Lin S, Liu D, Liang T, Zhuang Y, Wang X, Ma S, Li Q, Hu K.   +7 more
europepmc   +1 more source

Regulation of Treg cells by cytokine signaling and co-stimulatory molecules. [PDF]

Front Immunol
Zong Y, Deng K, Chong WP.
europepmc   +1 more source

Unlocking the Role of Treg Cells Immune Response and Infectious Risk Following CAR T-Cell Therapy in Patients with Cancer. [PDF]

Int J Mol Sci
Dicharry D, Malek AE.
europepmc   +1 more source