Validamycin Ingestion: A Rare Case of Poisoning With a Surprisingly Benign Outcome - Our Experience in a Resource-Limited Emergency Setting. [PDF]
Clin Case RepABSTRACT Validamycin ingestion is a rare encounter in emergency settings. There is no specific antidote, with management being largely symptomatic. Overzealous treatment and referral to higher centers are not necessary, as consumption of even large doses of Validamycin is non‐toxic to humans; rather, addressing the intention behind ingestion is more ...
Luitel A +5 more
europepmc +2 more sources
The secreted acid trehalase encoded by the CgATH1 gene is involved in Candida glabrata virulence [PDF]
Memorias do Instituto Oswaldo Cruz, 2020 BACKGROUND Candida glabrata yeast is the second cause of candidiasis worldwide. Differs from other yeasts since assimilates only glucose and trehalose (a characteristic used in rapid identification tests for this pathogen) by secreting into the medium a ...
Rafael G Lopes +5 more
doaj +2 more sources
Parasitoid Wasps Can Manipulate Host Trehalase to the Benefit of Their Offspring
Insects, 2022 Trehalase is an essential hydrolase of trehalose in insects. However, whether and how trehalase performs in the association of parasitoid wasps and their hosts still remains unknown. Here, the exact function of trehalase of the general cutworm Spodoptera
Yan Song +5 more
doaj +1 more source
Asymmetric trehalose analogues to probe disaccharide processing pathways in mycobacteria [PDF]
, 2020 The uptake and metabolism of the disaccharide trehalose by Mycobacterium tuberculosis is essential for the virulence of this pathogen. Here we describe the chemoenzymatic synthesis of new azido-functionalised asymmetric trehalose probes that resist ...
Fullam, Elizabeth +4 more
core +1 more source
C/EBPα Regulates PxTreh1 and PxTreh2 Trehalase-Related Bt Resistance in Plutella xylostella (L.)
Insects, 2022 Trehalase regulates energy metabolism in insects by converting trehalose into two glucose molecules. High amounts of trehalase are critical for insect flight and larval stress resistance.
Jia Liu +11 more
doaj +1 more source
Journal of Fungi, 2023 Sharp eyespot is a crucial disease affecting cereal plants, such as bread wheat (Triticum aestivum) and barley (Hordeum vulgare), and is primarily caused by the pathogenic fungus Rhizoctonia cerealis.
Xiaoyue Yang +9 more
doaj +1 more source
Trehalase localization in the cerebral cortex, hippocampus and cerebellum of mouse brains
Journal of Advanced Research, 2019 The non-reducing disaccharide trehalose is biosynthesized in several species but not in vertebrates. However, trehalase, the enzyme required for its cleavage, has been observed in different mammalian organs.
L. Halbe, A. Rami
doaj +1 more source
Insects, 2022 Trehalase is the only enzyme known for the irreversible splitting of trehalose and plays a major role in insect growth and development. In this report, we describe a basic study of the trehalase gene fragment encoding a soluble trehalase from ...
Qingtai Wang +7 more
doaj +1 more source
The dual nature of trehalose in citrus canker disease: A virulence factor for Xanthomonas citri subsp. citri and a trigger for plant defence responses [PDF]
, 2015 Xanthomonas citri subsp. citri (Xcc) is a bacterial pathogen that causes citrus canker in susceptible Citrus spp. The Xcc genome contains genes encoding enzymes from three separate pathways of trehalose biosynthesis.
Feil, Regina +10 more
core +1 more source
Virulence, 2022 Although four Shigella species (S. flexneri, S. sonnei, S. dysenteriae, and S. boydii) have been reported, S. sp. PAMC 28760, an Antarctica isolate, is the only one with a complete genome deposited in NCBI database as an uncharacterized isolate.
Prasansah Shrestha +4 more
doaj +1 more source