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Tremor may be defined as an involuntary movement that is rhythmic (ie, regularly recurrent) and oscillatory (ie, rotating around a central plane) and may manifest in a variety of ways; accordingly, tremor has a rich clinical phenomenology. Consequently, the diagnosis of tremor disorders can be challenging, and misdiagnoses are common.
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Rest tremor revisited: Parkinson’s disease and other disorders
Tremor is the most common movement disorder characterized by a rhythmical, involuntary oscillatory movement of a body part. Since distinct diseases can cause similar tremor manifestations and vice-versa, it is challenging to make an accurate diagnosis ...
Wei Chen +3 more
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Cerebello-thalamic activity drives an abnormal motor network into dystonic tremor
Dystonic tremor syndromes are highly burdensome and treatment is often inadequate. This is partly due to poor understanding of the underlying pathophysiology. Several lines of research suggest involvement of the cerebello-thalamo-cortical circuit and the
Freek Nieuwhof +8 more
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Animal Models of Tremor: Relevance to Human Tremor Disorders
ackground: Tremor is the most common movement disorder; however, the pathophysiology of tremor remains elusive. While several neuropathological alterations in tremor disorders have been observed in post-mortem studies of human brains, a full ...
Ming-Kai Pan +4 more
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Tremor Syndromes: An Updated Review
Tremor is the most commonly encountered movement disorder in clinical practice. A wide range of pathologies may manifest with tremor either as a presenting or predominant symptom.
Abhishek Lenka, Joseph Jankovic
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Tremor in a Bassoonist: Tremor in Dystonia or Essential Tremor?
Dear Editor, Tremor is a common clinical feature in dystonia. It can be seen in both affected and unaffected body parts in patients with dystonia. Clinically, it may not be easily distinguishable from essential tremor, currently defined as a bilateral, largely symmetric postural or kinetic tremor involving the hands and forearms that is visible and ...
Park, Jung E +2 more
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How to do an electrophysiological study of tremor
The electrophysiological characterization of hand tremors is a useful method to complement the history and physical exam of tremor patients. Our article describes the methodology (recording, processing and interpretation) used in a diagnostic/phenotypic ...
Felipe Vial +4 more
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Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication.
Zena Fadel +5 more
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Development of Harmaline-induced Tremor in a Swine Model
Background: In the field of translational neuroscience research, it is critical to utilize a large animal model to test the feasibility, safety, and functionality of novel therapies.
Jihyun Lee +7 more
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Quantification of tremor severity with a mobile tremor pen
Background: An objective evaluation of tremor severity is necessary to document the course of disease, the efficacy of treatment, or interventions in clinical trials. Most available objective quantification devices are complex, immobile, or not validated.
Tibor Zajki-Zechmeister +8 more
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