Results 31 to 40 of about 23,786 (209)

Pyruvate oxidation by Treponema pallidum [PDF]

Infection and Immunity, 1979
Cell-free extracts of Treponema pallidum catalyzed the decarboxylation of pyruvate. This activity was suppressed at low O2 tensions and appeared to be coenzyme A independent. Pyruvate decarboxylation was inorganic phosphate dependent, and evidence suggested that acetyl phosphate was a product.
J T, Barbieri, C D, Cox
openaire   +2 more sources

Há 100 anos, a descoberta do Treponema pallidum A hundred years ago, the discovery of Treponema pallidum

Anais Brasileiros de Dermatologia, 2005
A descoberta do Treponema pallidum por Schaudinn & Hoffmann em 3 de março de 1905 foi influenciada pela comunicação de Siegel, sobre a descoberta do agente etiológico da sífilis.
Elemir Macedo de Souza
doaj   +1 more source

A clustered regularly interspaced palindromic repeat‐Cas12a‐based assay for rapid dengue virus monitoring in mosquito and clinical samples facilitating global collaborative surveillance and risk assessment to block dengue spreading

Interdisciplinary Medicine, EarlyView.
The RAA‐Cas12a assay outperforms real‐time PCR in sensitivity (92.3%) while matching its specificity (100%) for dengue virus detection in clinical samples. It effectively identifies DENV in mosquitoes, with field data correlating to local outbreaks. This rapid, simple, and precise method serves as an early warning tool for dengue management.
Xiang Guo, Minling Hu, Ying Lu, Xiaohua Liu, Haiyang Chen, Xiaoqing Zhang, Liu Ge, Ziyao Li, Yuji Wang, Qing He, Shu Zeng, Wenwen Ren, Lingzhai Zhao, Zhiqiang Peng, Wushen Chen, Chunmei Wang, Qingming Kong, Shaohong Lu, Fuchun Zhang, Lei Luo, Hua Li, Xiao‐Guang Chen, Xiaohong Zhou   +22 more
wiley   +1 more source

The pan-genome of Treponema pallidum reveals differences in genome plasticity between subspecies related to venereal and non-venereal syphilis

BMC Genomics, 2020
Background Spirochetal organisms of the Treponema genus are responsible for causing Treponematoses. Pathogenic treponemes is a Gram-negative, motile, spirochete pathogen that causes syphilis in human. Treponema pallidum subsp.
Arun Kumar Jaiswal, Sandeep Tiwari, Syed Babar Jamal, Letícia de Castro Oliveira, Leandro Gomes Alves, Vasco Azevedo, Preetam Ghosh, Carlo Jose Freira Oliveira, Siomar C. Soares   +8 more
doaj   +1 more source

Epidemic of venereal treponematosis in wild monkeys: a paradigm for syphilis origin

New Microbes and New Infections, 2020
Treponema pallidum infections have been primarily known as slightly contagious mucocutaneous infections called yaws (tropical Africa and America) and bejel (subtropical North Africa). T.
O. Mediannikov, F. Fenollar, B. Davoust, N. Amanzougaghene, H. Lepidi, J.-P. Arzouni, G. Diatta, C. Sokhna, J. Delerce, A. Levasseur, D. Raoult   +10 more
doaj   +1 more source

Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete.

PLoS Pathogens, 2021
Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful.
Emily Romeis, Lauren Tantalo, Nicole Lieberman, Quynh Phung, Alex Greninger, Lorenzo Giacani   +5 more
doaj   +1 more source

Canadian Public Health Laboratory Network Laboratory Guidelines for the Use of Direct Tests to Detect Syphilis in Canada

Canadian Journal of Infectious Diseases and Medical Microbiology, 2015
Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T.
Raymond SW Tsang, Muhammad Morshed, Max A Chernesky, Gayatri C Jayaraman, Kamran Kadkhoda   +4 more
doaj   +1 more source

Detection of Treponema pallidum subspecies pallidum for the diagnosis of congenital syphilis by nested polymerase chain reaction

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction. Syphilis is a disease produced by Treponema pallidum subspecies pallidum, which affects approximately 12 million people worldwide every year.
Gladys Pinilla, Lesly Campos, Andrea Durán, Jeannette Navarrete, Liliana Muñoz   +4 more
doaj   +1 more source

The Treponema pallidum Outer Membrane [PDF]

, 2017
The outer membrane (OM) of Treponema pallidum, the uncultivatable agent of venereal syphilis, has long been the subject of misconceptions and controversy. Decades ago, researchers postulated that T. pallidum's poor surface antigenicity is the basis for its ability to cause persistent infection, but they mistakenly attributed this enigmatic property to ...
Justin D, Radolf, Sanjiv, Kumar
openaire   +2 more sources

Mucopolysaccharidase of Treponema pallidum [PDF]

Infection and Immunity, 1979
Treponema pallidum (Nichols strain) exhibited mucopolysaccharidase activity. Acidic mucopolysaccharides were broken down more rapidly by viable treponemes than by heat-inactivated treponemes or membrane filtrates of treponemal suspensions.
T J, Fitzgerald, R C, Johnson
openaire   +2 more sources