Results 41 to 50 of about 63,007 (294)
Molecular typing of Treponema pallidum isolates from Buenos Aires, Argentina: Frequent Nichols-like isolates and low levels of macrolide resistance [PDF]
, 2017 A total of 54 clinical samples, including genital lesion swabs, whole blood and cerebrospinal fluid from patients diagnosed with syphilis were collected in 2006 and in 2013 in Buenos Aires, Argentina.
Casco, Ricardo +6 more
core +1 more source
The molecular epidemiology of Treponema pallidum subspecies pallidum [PDF]
Sexual Health, 2015 Pathogens adapt and evolve in response to pressures exerted by host environments, leading to generation of genetically diverse variants. Treponema pallidum subspecies pallidum displays a substantial amount of interstrain diversity. These variants have been identified in various parts of the world, indicating transmission linkage between geographical ...
Daphne Y. Ma +2 more
openaire +3 more sources
Clinical Infectious Diseases, 2020 Direct detection methods for Treponema pallidum include dark-field microscopy (DFM), direct fluorescence antibody (DFA) testing, immunohistochemistry (IHC), and nucleic acid amplification tests (NAATs).
E. Theel, Samantha S. Katz, A. Pillay
semanticscholar +1 more source
PLoS Pathogens, 2021 Treponema pallidum ssp. pallidum, the causative agent of syphilis, can now be cultured continuously in vitro utilizing a tissue culture system, and the multiplication rates are similar to those obtained in experimental infection of rabbits. In this study,
Bridget D De Lay +4 more
semanticscholar +1 more source
BMC Infectious Diseases, 2020 Background The syphilis epidemic continues to cause substantial morbidity and mortality worldwide, particularly in low- and middle-income countries, despite several recent disease control initiatives.
Ethan Osias +11 more
doaj +1 more source
Cryo-Electron Tomography Elucidates the Molecular Architecture of Treponema pallidum, the Syphilis Spirochete [PDF]
, 2009 Cryo-electron tomography (CET) was used to examine the native cellular organization of Treponema pallidum, the syphilis spirochete. T. pallidum cells appeared to form flat waves, did not contain an outer coat and, except for bulges over the basal bodies ...
Cox, David L. +10 more
core +3 more sources
Pyruvate oxidation by Treponema pallidum [PDF]
Infection and Immunity, 1979 Cell-free extracts of Treponema pallidum catalyzed the decarboxylation of pyruvate. This activity was suppressed at low O2 tensions and appeared to be coenzyme A independent. Pyruvate decarboxylation was inorganic phosphate dependent, and evidence suggested that acetyl phosphate was a product.
C D Cox, Joseph T. Barbieri
openaire +3 more sources
bioRxiv, 2021 Syphilis is a sexually transmitted, disseminated acute and chronic infection caused by the bacterial pathogen Treponema pallidum subspecies pallidum. Primary syphilis typically presents as single or multiple mucocutaneous lesions and, if left untreated ...
Charles M. Thurlow +19 more
semanticscholar +1 more source
Spirochetal Lipoproteins and Immune Evasion. [PDF]
, 2017 Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
core +1 more source
Journal of Clinical Microbiology, 2021 This study evaluated the performance characteristics of a new research-use-only transcription-mediated amplification (TMA) assay for the detection of rRNA from Treponema pallidum.
D. Getman +8 more
semanticscholar +1 more source