Results 21 to 30 of about 935 (139)

Yaws in Africa: Past, Present and Future [PDF]

Diseases
Background: Yaws is an infectious, neglected tropical disease that affects the skin of many children and adolescents who live in poor, rural, low-income communities in humid, tropical areas of Africa, Southeast Asia, and the Pacific Islands.
Ezekiel K. Vicar, Shirley V. Simpson, Gloria I. Mensah, Kennedy K. Addo, Eric S. Donkor   +4 more
doaj   +2 more sources

Whole genome sequence of the Treponema pallidum subsp. endemicum strain Iraq B: A subpopulation of bejel treponemes contains full-length tprF and tprG genes similar to those present in T. p. subsp. pertenue strains.

PLoS ONE, 2020
Treponema pallidum subsp. endemicum (TEN) is the causative agent of endemic syphilis (bejel). Until now, only a single TEN strain, Bosnia A, has been completely sequenced.
Lenka Mikalová, Klára Janečková, Markéta Nováková, Michal Strouhal, Darina Čejková, Kristin N Harper, David Šmajs   +6 more
doaj   +4 more sources

Ancient genomes reveal a deep history of Treponema pallidum in the Americas. [PDF]

Nature
Human treponemal infections are caused by a family of closely related Treponema pallidum that give rise to the diseases yaws, bejel, pinta and, most famously, syphilis.
Barquera R, Sitter TL, Kirkpatrick CL, Ramirez DA, Kocher A, Spyrou MA, Couoh LR, Talavera-González JA, Castro M, von Hunnius T, Guevara EK, Hamilton WD, Roberts P, Scott E, Fabra M, Da Peña GV, Pacheco A, Rodriguez M, Aspillaga E, Tiliakou A, Nelson EA, Giffin KL, Bianco RA, Rohrlach AB, de Los Ángeles García Martínez M, Ballesteros Solís FA, Sajantila A, Saunders SR, Nores R, Herbig A, Krause J, Bos KI.   +31 more
europepmc   +6 more sources

Whole genome sequence of the Treponema Fribourg- Blanc: Unspecified simian isolate is highly similar to the yaws subspecies [PDF]

, 2013
BACKGROUND:Unclassified simian strain Treponema Fribourg-Blanc was isolated in 1966 from baboons (Papio cynocephalus) in West Africa. This strain was morphologically indistinguishable from T. pallidum ssp. pallidum or ssp.
Ambrozova, Lenka, Cejkova, Darina, Chen, Lei, Fulton, Lucinda L, Mikalova, Lenka, Pospisilova, Petra, Smajs, David, Sodergren, Erica, Strouhal, Michal, Weinstock, George M, Zobanikova, Marie   +10 more
core   +27 more sources

Whole-genome sequencing reveals evidence for inter-species transmission of the yaws bacterium among nonhuman primates in Tanzania. [PDF]

PLoS Negl Trop Dis
Background Treponema pallidum subspecies pertenue (TPE) is the causative agent of human and nonhuman primate (NHP) yaws infection. The discovery of yaws bacterium in wild populations of NHPs opened the question of transmission mechanisms within NHPs, and
Janečková K, Roos C, Andrla P, Fedrová P, Tom N, Lueert S, Keyyu JD, Chuma IS, Šmajs D, Knauf S.   +9 more
europepmc   +3 more sources

Seroprevalence and geospatial epidemiology of yaws: Evidence from Ghana. [PDF]

PLoS Neglected Tropical Diseases
BackgroundYaws, a neglected tropical disease caused by Treponema pallidum subsp. pertenue remains a public health challenge in endemic regions. Although the World Health Organization (WHO) has earmarked yaws for eradication by the year 2030, there is a ...
Abigail Agbanyo, Michael Ntiamoah Oppong, Ruth Dede Tuwor, Shadrach Mintah, Victor Yaw Morgan, Clement Tettey, Joseph Azabire, Owusu Boakye Yiadom, Dennis Odai Laryea, Alex Owusu-Ofori, Yaw Ampem Amoako, Richard Odame Phillips   +11 more
doaj   +2 more sources

Low genetic diversity of Treponema pallidum ssp. pertenue (TPE) isolated from patients' ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes. [PDF]

PLoS Neglected Tropical Diseases
Yaws is an endemic disease caused by Treponema pallidum subsp. pertenue (TPE) that primarily affects children in rural regions of the tropics. The endemic character of yaws infections and the expected exclusive reservoir of TPE in humans opened a new ...
Monica Medappa, Petra Pospíšilová, Maria Paula M Madruga, Lucy N John, Camila G Beiras, Linda Grillová, Jan Oppelt, Arka Banerjee, Marti Vall-Mayans, Oriol Mitjà, David Šmajs   +10 more
doaj   +2 more sources

Treponema pallidumsubsp.pertenueDisplays Pathogenic Properties Different from Those ofT. pallidumsubsp.pallidum [PDF]

Infection and Immunity, 2000
ABSTRACTThe present study described the susceptibility of C4D guinea pigs to cutaneous infection withTreponema pallidumsubsp.pertenueHaiti B strain. The general manifestations of the disease in adults and neonates differ, to a certain degree, from those induced byT. pallidumsubsp.pallidumNichols strain.
K, Wicher, V, Wicher, F, Abbruscato, R E, Baughn   +3 more
openaire   +2 more sources

Molecular strain typing of the yaws pathogen, Treponema pallidum subspecies pertenue. [PDF]

PLoS ONE, 2018
Yaws is a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue. The disease primarily affects children under 15 years of age living in low socioeconomic conditions in tropical areas.
Samantha S Katz, Kai-Hua Chi, Eli Nachamkin, Damien Danavall, Fasihah Taleo, Jacob L Kool, Kennedy Kwasi Addo, William Ampofo, Shirley V Simpson, Tun Ye, Kingsley B Asiedu, Ronald C Ballard, Cheng Y Chen, Allan Pillay   +13 more
doaj   +1 more source

The pan-genome of Treponema pallidum reveals differences in genome plasticity between subspecies related to venereal and non-venereal syphilis

BMC Genomics, 2020
Background Spirochetal organisms of the Treponema genus are responsible for causing Treponematoses. Pathogenic treponemes is a Gram-negative, motile, spirochete pathogen that causes syphilis in human. Treponema pallidum subsp.
Arun Kumar Jaiswal, Sandeep Tiwari, Syed Babar Jamal, Letícia de Castro Oliveira, Leandro Gomes Alves, Vasco Azevedo, Preetam Ghosh, Carlo Jose Freira Oliveira, Siomar C. Soares   +8 more
doaj   +1 more source