Results 91 to 100 of about 4,397 (170)

Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1

Nature Communications, 2018
The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of ...
James M. Dunce, Amy E. Milburn, Manickam Gurusaran, Irene da Cruz, Lee T. Sen, Ricardo Benavente, Owen R. Davies   +6 more
doaj   +1 more source

Identification of a Tankyrase-binding Motif Shared by IRAP, TAB182, and Human TRF1 but Not Mouse TRF1 [PDF]

Journal of Biological Chemistry, 2002
Juan I. Sbodio, Nai-Wen Chi
openaire   +1 more source

TRF1: It Was the Best of Time(s)… [PDF]

Timing & Time Perception, 2018
Anne Giersch, Jennifer T. Coull
openaire   +1 more source

Human liver cell trafficking mutants: characterization and whole exome sequencing.

PLoS ONE, 2014
The HuH7 liver cell mutant Trf1 is defective in membrane trafficking and is complemented by the casein kinase 2α subunit CK2α''. Here we identify characteristic morphologies, trafficking and mutational changes in six additional HuH7 mutants Trf2-Trf7 ...
Fei Yuan, Erik L Snapp, Phyllis M Novikoff, Sylvia O Suadicani, David C Spray, Barry Potvin, Allan W Wolkoff, Pamela Stanley   +7 more
doaj   +1 more source

Molecular Dynamics Simulation of Telomere and TRF1 [PDF]

Proceedings of the 12th Asia Pacific Physics Conference (APPC12), 2014
Masaaki Kaburagi, Masaki Fukuda, Hironao Yamada, Takeshi Miyakawa, Ryota Morikawa, Masako Takasu, Takamitsu A. Kato, Mitsuru Uesaka   +7 more
openaire   +1 more source

Macrophage-derived exosomes promote telomere fragility and senescence in tubular epithelial cells by delivering miR-155

Cell Communication and Signaling
Background Chronic kidney disease (CKD) is highly prevalent worldwide, and its global burden is substantial and growing. CKD displays a number of features of accelerated senescence.
Qing Yin, Tao-Tao Tang, Xiao-Yu Lu, Wei-Jie Ni, Di Yin, Yi-Lin Zhang, Wei Jiang, Yue Zhang, Zuo-Lin Li, Yi Wen, Wei-Hua Gan, Ai-Qing Zhang, Lin-Li Lv, Bin Wang, Bi-Cheng Liu   +14 more
doaj   +1 more source

Orphan nuclear receptors recruit TRIM28 to promote telomeric H3K9me3 for the ALT pathway. [PDF]

EMBO J
Tsai CT, Gaela VM, Hsia HY, Huang YC, Shen YL, Chen LY.   +5 more
europepmc   +1 more source

TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere [PDF]

Biophysical Journal, 2019
Hai Pan, Saroj Dangi, Parminder Kaur, Pengyu Hao, Keith Weninger, Robert Riehn, Patricia Opresko, Hong Wang   +7 more
openaire   +1 more source

Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells. [PDF]

Nat Cell Biol
Markiewicz-Potoczny M, Lee SY, Chatterjee S, Mabin JW, Zinsser A, Sandhu R, Tricola G, Hogg JR, Lazzerini Denchi E.   +8 more
europepmc   +1 more source

ESCO2 Interacts with TRF1/2 and Facilitates Telomere Maintenance. [PDF]

Int J Mol Sci
Guo J, Ji J, Liu J, Tang M.
europepmc   +1 more source