Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
Chemistry &Biodiversity, EarlyView.ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source
Carbon and Hydrogen, EarlyView.Efficient synthesis of methyl ethyl carbonate from dimethyl carbonate and ethanol catalyzed by ionic liquid [EMIM]ATZ at room temperature. ABSTRACT This study reports the development of a novel amino‐functionalized ionic liquid catalyst, namely 1‐butyl‐3‐methylimidazolium amino triazole ([EMIM]ATZ), for the efficient and sustainable synthesis of ethyl ...
Peixue Wang +6 more
wiley +1 more source
Poly(ethylene Glycol)‐Based Peptidomimetics (Pegtides) of Antimicrobial Peptides
ChemBioChem, EarlyView.Polyethylene glycol (PEG) is commonly used to improve the pharmacokinetics and pharmacodynamics of therapeutic candidates by conjugation. Here PEG is exploited for peptidomimetic conversion of antimicrobial peptides (AMPs), as candidate antibacterial agents, by replacing their polyamide backbone. The pegtides obtained thereby can be readily synthesized
Conor Shine +13 more
wiley +1 more source
Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research
ChemBioChem, EarlyView.The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley +1 more source
ChemistryEurope, EarlyView.Novel amido‐enaminone threads efficiently template the formation of hydrogen‐bonded [2]rotaxanes and enable diverse postsynthetic modifications. Benzyl groups promote diastereoselective cyclizations to interlocked lactams while the enaminone motif allows stopper exchange while preserving the mechanical bond.
Syed S. Razi +4 more
wiley +1 more source
Gas phase flash pyrolysis of 3-azido-1,2,4-triazole: generation and ultraviolet photoelectron spectrum of N-cyanomethanimine [PDF]
, 1988 I. B'Shary +4 more
openalex +1 more source
A halogen bonding BODIPY-appended aza-crown ether for selective optical sensing of inorganic and organic ion-pair species. [PDF]
Chem SciWilmore JT +4 more
europepmc +1 more source
Recent Progress in the Preparation of Graphdiyne‐Based Materials
ChemistryEurope, EarlyView.Graphdiyne (GDY) has emerged as a versatile carbon allotrope for cutting‐edge applications. To fully unlock the distinguished characteristics of GDY‐based materials, precise preparation is vital for structure control, which largely shapes the materials’ properties.
Ruiqiao Wu +5 more
wiley +1 more source
Rational design of indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors featuring 1,2,3-triazole derivatives with enhanced anti-inflammatory and analgesic efficacy. [PDF]
Front PharmacolLiu Q +6 more
europepmc +1 more source