Results 141 to 150 of about 81,191 (254)

Metformin-improved cognitive impairment in patients with schizophrenia is correlated with activation of tricarboxylic acid cycle and restored functional connectivity of hippocampus. [PDF]

BMC Med
Cai J, Xiao J, Long Y, Cao T, Lin C, Hei G, Wang W, Kang D, Huang J, Shao T, Cai H, Wu R.   +11 more
europepmc   +1 more source

Determiners of cell fates: the tricarboxylic acid cycle versus the citrate-malate shuttle. [PDF]

Protein Cell, 2023
Guo D, He H, Meng Y, Luo S, Lu Z.
europepmc   +1 more source

The Metabolism of Pyruvate in the Tricarboxylic Acid Cycle

Journal of Biological Chemistry, 1958
A D, FREEDMAN, S, GRAFF
openaire   +2 more sources

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle. [PDF]

Redox Biol
Yegambaram M, Sun X, Lu Q, Flores AG, Zemskova M, Soto J, Rauckhorst A, Maltepe E, Wang T, Fineman JR, Black SM.   +10 more
europepmc   +1 more source

An all‐in‐one fucosylated gold nanocluster probe enables NIR‐II imaging and multi‐mechanistic therapy of acute kidney injury

BMEMat, EarlyView.
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang, Boning Tan, Suqing Feng, Beibei Gu, Ting Feng, Haiguang Zhu, Jianping Xie, Xun Yuan   +7 more
wiley   +1 more source

Lactate activates trained immunity by fueling the tricarboxylic acid cycle and regulating histone lactylation. [PDF]

Nat Commun
Cai H, Chen X, Liu Y, Chen Y, Zhong G, Chen X, Rong S, Zeng H, Zhang L, Li Z, Liao A, Zeng X, Xiong W, Guo C, Zhu Y, Deng KQ, Ren H, Yan H, Cai Z, Xu K, Zhou L, Lu Z, Wang F, Liu S.   +23 more
europepmc   +1 more source

Mid-infrared Photons Released by NAD⁺ Reduction in the Tricarboxylic Acid Cycle of Myelinated Neuron. [PDF]

Neurosci Bull, 2023
Peng D, Qi W, Zhang F, Song B.
europepmc   +1 more source

Infrared Laser Heating Reveals a Reversible Phase Transition of Phosphofructokinase 1 in Mammalian Cells

Chemistry – A European Journal, EarlyView.
In this study, we present a novel method to investigate the phase behavior of biomolecular condensates in living cells. The method complements FRAP experiments, expanding the existing toolbox for characterization of condensates within living cells. ABSTRACT Metabolic enzymes can operate in concerted networks, so‐called metabolons.
Morten Mosbach, Sneha Pavanan Kuruvanthara, Lukas Johannknecht, Simon Ebbinghaus   +3 more
wiley   +1 more source

Hypoxia-inducible APCDD1L-AS1 promotes osimertinib resistance by stabilising DLST to drive tricarboxylic acid cycle in lung adenocarcinoma. [PDF]

J Exp Clin Cancer Res
Zhang Q, Shen Y, Che Y, Jia L, Xiao X, Xu H, Su C, Sun K, Zheng L, Xu J, Hu J, Zhang C, Zhu D, Li M.   +13 more
europepmc   +1 more source