Results 11 to 20 of about 73,690 (159)
Regulation and function of the mammalian tricarboxylic acid cycle. [PDF]
J Biol Chem, 2023 Arnold PK, Finley LWS.
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The Role of Tricarboxylic Acid Cycle Metabolites in Viral Infections
Frontiers in Cellular and Infection Microbiology, 2021 Host cell metabolism is essential for the viral replication cycle and, therefore, for productive infection. Energy (ATP) is required for the receptor-mediated attachment of viral particles to susceptible cells and for their entry into the cytoplasm. Host
Francisco Javier Sánchez-García +3 more
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Molecules, 2023 When the expression of NOS2 in M1-polarized macrophages is induced, huge amounts of nitric oxide (•NO) are produced from arginine and molecular oxygen as the substrates.
Junichi Fujii, Tsukasa Osaki
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Role of Oxidative Stress in Mitochondrial Function: Relevance for Liver Function
Antioxidants, 2023 The traditional recognition of mitochondria as powerhouses that generate ATP and reactive oxygen species (ROS) via oxidative phosphorylation and the tricarboxylic acid cycle has ceased [...]
Jie Xu, Zhihui Feng
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Frontiers in Fungal Biology, 2022 The growth and development of organisms depend on nutrient availability. Dermatophytes must sense nutrient levels and adapt to the host environment to colonize human and animal keratinized tissues.
Aline H. S. Cruz +9 more
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Molecular Metabolism, 2022 Objectives: Glucocorticoids (GCs) are one of the most widely prescribed anti-inflammatory drugs. By acting through their cognate receptor, the glucocorticoid receptor (GR), GCs downregulate the expression of pro-inflammatory genes and upregulate the ...
Ulrich Stifel +15 more
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Ketogenic diet in action: Metabolic profiling of pyruvate dehydrogenase deficiency
Molecular Genetics and Metabolism Reports, 2023 The pyruvate dehydrogenase complex serves as the main connection between cytosolic glycolysis and the tricarboxylic acid cycle within mitochondria. An infant with pyruvate dehydrogenase complex deficiency was treated with vitamin B1 supplementation and a
Eri Ogawa +6 more
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Edwardsiella tarda Tunes Tricarboxylic Acid Cycle to Evade Complement-Mediated Killing
Frontiers in Immunology, 2017 Evasion of complement-mediated killing is a common phenotype for many different types of pathogens, but the mechanism is still poorly understood. Most of the clinic isolates of Edwardsiella tarda, an important pathogen infecting both of human and fish ...
Zhi-xue Cheng +10 more
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Chromatin remodeling factor LSH affects fumarate hydratase as a cancer driver
Chinese Journal of Cancer, 2016 Cancer metabolism and epigenetic alteration are two critical mechanisms for tumorigenesis and cancer progression; however, the dynamic interplay between them remains poorly understood.
Shuang Liu, Yong-Guang Tao
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PLoS Pathogens, 2020 The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T.
William J Olson +6 more
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