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The Utilization by Yeasts of Acids of the Tricarboxylic Acid Cycle [PDF]
SUMMARY: Growth and respiration on intermediates of the tricarboxylic acid cycle as sole sources of carbon were studied with a number of different yeasts. The incorporation of [1:2-14C]acetate by acetate-respiring cells was studied with yeasts capable of utilizing exogenously supplied cycle intermediates (K+) and also with those unable to do so (K ...
J A, BARNETT, H L, KORNBERG
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Chromatin remodeling factor LSH affects fumarate hydratase as a cancer driver
Cancer metabolism and epigenetic alteration are two critical mechanisms for tumorigenesis and cancer progression; however, the dynamic interplay between them remains poorly understood.
Shuang Liu, Yong-Guang Tao
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The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T.
William J Olson +6 more
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Acetobacter pasteurianus is always used to brew vinegar because of its ability of producing and tolerating a high concentration of acetic acid. During vinegar fermentation, initial acetic acid contributes to acetic acid accumulation, which varies with ...
Tian Li +5 more
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Biochemical and Metabolic Implications of Tricarboxylic Acids and their Transporters
Tricarboxylic acid cycle is the essential metabolic pathway for cellular biosynthetic processes e.g. gluconeogenesis, amino acid and heme biosynthesis.
Khalifa El-Dawy +3 more
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Regulation of Mitochondrial Respiration by Hydrogen Sulfide
Hydrogen sulfide (H2S), the third gasotransmitter, has positive roles in animals and plants. Mitochondria are the source and the target of H2S and the regulatory hub in metabolism, stress, and disease.
Dandan Huang, Guangqin Jing, Shuhua Zhu
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A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle).
Vinai Chittezham Thomas +14 more
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The Tricarboxylic Acid Cycle in Nematode Parasites [PDF]
IN nematode parasites the anaerobic breakdown of glycogen to pyruvate and lactate with a consequent formation of adenosine triphosphate follows a course similar to that in vertebrate muscle1. Since it appears that aerobic mechanisms may play an important part in the metabolism of certain nematode parasites2, studies on the carbohydrate metabolism of ...
V, MASSEY, W P, ROGERS
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Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
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The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. [PDF]
The tricarboxylic acid (TCA) cycle is an essential metabolic network in all oxidative organisms and provides precursors for anabolic processes and reducing factors (NADH and FADH(2)) that drive the generation of energy.
Ryan J Mailloux +6 more
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