Results 21 to 30 of about 81,191 (254)

The Utilization by Yeasts of Acids of the Tricarboxylic Acid Cycle [PDF]

open access: yesJournal of General Microbiology, 1960
SUMMARY: Growth and respiration on intermediates of the tricarboxylic acid cycle as sole sources of carbon were studied with a number of different yeasts. The incorporation of [1:2-14C]acetate by acetate-respiring cells was studied with yeasts capable of utilizing exogenously supplied cycle intermediates (K+) and also with those unable to do so (K ...
J A, BARNETT, H L, KORNBERG
openaire   +2 more sources

Chromatin remodeling factor LSH affects fumarate hydratase as a cancer driver

open access: yesChinese Journal of Cancer, 2016
Cancer metabolism and epigenetic alteration are two critical mechanisms for tumorigenesis and cancer progression; however, the dynamic interplay between them remains poorly understood.
Shuang Liu, Yong-Guang Tao
doaj   +1 more source

Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability.

open access: yesPLoS Pathogens, 2020
The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T.
William J Olson   +6 more
doaj   +1 more source

Investigation of Acid Tolerance Mechanism of Acetobacter pasteurianus under Different Concentrations of Substrate Acetic Acid Based on 4D Label-Free Proteomic Analysis

open access: yesFoods, 2023
Acetobacter pasteurianus is always used to brew vinegar because of its ability of producing and tolerating a high concentration of acetic acid. During vinegar fermentation, initial acetic acid contributes to acetic acid accumulation, which varies with ...
Tian Li   +5 more
doaj   +1 more source

Biochemical and Metabolic Implications of Tricarboxylic Acids and their Transporters

open access: yesJournal of Pure and Applied Microbiology, 2019
Tricarboxylic acid cycle is the essential metabolic pathway for cellular biosynthetic processes e.g. gluconeogenesis, amino acid and heme biosynthesis.
Khalifa El-Dawy   +3 more
doaj   +1 more source

Regulation of Mitochondrial Respiration by Hydrogen Sulfide

open access: yesAntioxidants, 2023
Hydrogen sulfide (H2S), the third gasotransmitter, has positive roles in animals and plants. Mitochondria are the source and the target of H2S and the regulatory hub in metabolism, stress, and disease.
Dandan Huang, Guangqin Jing, Shuhua Zhu
doaj   +1 more source

A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β-Lactam Stress

open access: yesmBio, 2013
A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle).
Vinai Chittezham Thomas   +14 more
doaj   +1 more source

The Tricarboxylic Acid Cycle in Nematode Parasites [PDF]

open access: yesNature, 1949
IN nematode parasites the anaerobic breakdown of glycogen to pyruvate and lactate with a consequent formation of adenosine triphosphate follows a course similar to that in vertebrate muscle1. Since it appears that aerobic mechanisms may play an important part in the metabolism of certain nematode parasites2, studies on the carbohydrate metabolism of ...
V, MASSEY, W P, ROGERS
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. [PDF]

open access: yesPLoS ONE, 2007
The tricarboxylic acid (TCA) cycle is an essential metabolic network in all oxidative organisms and provides precursors for anabolic processes and reducing factors (NADH and FADH(2)) that drive the generation of energy.
Ryan J Mailloux   +6 more
doaj   +1 more source

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