Results 21 to 30 of about 73,690 (159)

Investigation of Acid Tolerance Mechanism of Acetobacter pasteurianus under Different Concentrations of Substrate Acetic Acid Based on 4D Label-Free Proteomic Analysis

Foods, 2023
Acetobacter pasteurianus is always used to brew vinegar because of its ability of producing and tolerating a high concentration of acetic acid. During vinegar fermentation, initial acetic acid contributes to acetic acid accumulation, which varies with ...
Tian Li, Xinwei Wang, Chunyan Li, Qingquan Fu, Xuewei Shi, Bin Wang   +5 more
doaj   +1 more source

Biochemical and Metabolic Implications of Tricarboxylic Acids and their Transporters

Journal of Pure and Applied Microbiology, 2019
Tricarboxylic acid cycle is the essential metabolic pathway for cellular biosynthetic processes e.g. gluconeogenesis, amino acid and heme biosynthesis.
Khalifa El-Dawy, Ashraf S.A El-Sayed, Sara A. El-Hefnawy, Nermeen M. El-Kahky   +3 more
doaj   +1 more source

Regulation of Mitochondrial Respiration by Hydrogen Sulfide

Antioxidants, 2023
Hydrogen sulfide (H2S), the third gasotransmitter, has positive roles in animals and plants. Mitochondria are the source and the target of H2S and the regulatory hub in metabolism, stress, and disease.
Dandan Huang, Guangqin Jing, Shuhua Zhu
doaj   +1 more source

A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β-Lactam Stress

mBio, 2013
A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle).
Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, Paul D. Fey   +14 more
doaj   +1 more source

Mitochondrial TrxR2 regulates metabolism and protects from metabolic disease through enhanced TCA and ETC function

Communications Biology, 2022
TrxR2 overexpression in mice enhances metabolism and prevents high-fat diet induced metabolic deficits in mice through alteration in function of several enzymes in the tricarboxylic acid cycle and complexes of the electron transport chain.
E. Sandra Chocron, Kennedy Mdaki, Nisi Jiang, Jodie Cropper, Andrew M. Pickering   +4 more
doaj   +1 more source

The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. [PDF]

PLoS ONE, 2007
The tricarboxylic acid (TCA) cycle is an essential metabolic network in all oxidative organisms and provides precursors for anabolic processes and reducing factors (NADH and FADH(2)) that drive the generation of energy.
Ryan J Mailloux, Robin Bériault, Joseph Lemire, Ranji Singh, Daniel R Chénier, Robert D Hamel, Vasu D Appanna   +6 more
doaj   +1 more source

Electrochemical gating of tricarboxylic acid cycle in electricity-producing bacterial cells of Shewanella. [PDF]

PLoS ONE, 2013
Energy-conversion systems mediated by bacterial metabolism have recently attracted much attention, and therefore, demands for tuning of bacterial metabolism are increasing.
Shoichi Matsuda, Huan Liu, Atsushi Kouzuma, Kazuya Watanabe, Kazuhito Hashimoto, Shuji Nakanishi   +5 more
doaj   +1 more source

Clofibrate elevates enzyme activities of the tricarboxylic acid cycle in rat liver.

Journal of Lipid Research, 1993
Activities of the tricarboxylic acid cycle enzymes were measured in subcellular fractions of liver from rats that had been fed clofibrate for 3 weeks. Large changes in these activities per gram tissue were found in the large particle fraction, which also
C Prager, HJ Schön, M Nikfardjam, D Schmid, M Untersalmberger, K Kremser, R Kramar   +6 more
doaj   +1 more source

Protein-protein interactions and metabolite channelling in the plant tricarboxylic acid cycle

Nature Communications, 2017
A metabolon is a complex of sequential metabolic enzymes that channels substrates directly between enzymes, thus optimizing metabolic flux. Here Zhanget al.
Youjun Zhang, Katherine F. M. Beard, Corné Swart, Susan Bergmann, Ina Krahnert, Zoran Nikoloski, Alexander Graf, R. George Ratcliffe, Lee J. Sweetlove, Alisdair R. Fernie, Toshihiro Obata   +10 more
doaj   +1 more source

Kinetics of the ancestral carbon metabolism pathways in deep-branching bacteria and archaea

Communications Chemistry, 2021
The reductive tricarboxylic acid cycle and the reductive acetyl-CoA pathways are thought to be ancient carbon fixation pathways in deepbranching bacteria and archaea.
Tomonari Sumi, Kouji Harada
doaj   +1 more source