The early expansion and evolutionary dynamics of POU class genes. [PDF]
, 2014 The POU genes represent a diverse class of animal-specific transcription factors that play important roles in neurogenesis, pluripotency, and cell-type specification. Although previous attempts have been made to reconstruct the evolution of the POU class,
Gates, Ruth D +2 more
core +1 more source
Comparative genomics of large mitochondria in placozoans.
PLoS Genetics, 2007 The first sequenced mitochondrial genome of a placozoan, Trichoplax adhaerens, challenged the conventional wisdom that a compact mitochondrial genome is a common feature among all animals.
Ana Y Signorovitch +2 more
doaj +1 more source
Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human [PDF]
, 2018 Author Posting. © The Author(s), 2018. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution.
Fang, Bin +5 more
core +1 more source
Genome-wide analysis of transposable elements and tandem repeats in the compact placozoan genome
Biology Direct, 2010 The placozoan Trichoplax adhaerens has a compact genome with many primitive eumetazoan characteristics. In order to gain a better understanding of its genome architecture, we conducted a detailed analysis of repeat content in this genome.
Meyer Eli +3 more
doaj +1 more source
Communications Biology, 2023 ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib +7 more
doaj +1 more source
Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution [PDF]
PeerJ, 2017 Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria.
Jan Philipp Novotný +9 more
doaj +2 more sources
Deep RNA sequencing reveals the smallest known mitochondrial micro exon in animals: The placozoan cox1 single base pair exon. [PDF]
PLoS ONE, 2017 The phylum Placozoa holds a key position for our understanding of the evolution of mitochondrial genomes in Metazoa. Placozoans possess large mitochondrial genomes which harbor several remarkable characteristics such as a fragmented cox1 gene and trans ...
Hans-Jürgen Osigus +2 more
doaj +1 more source
Identification, distribution and molecular evolution of the pacifastin gene family in Metazoa [PDF]
, 2009 BACKGROUND: Members of the pacifastin family are serine peptidase inhibitors, most of which are produced as multi domain precursor proteins. Structural and biochemical characteristics of insect pacifastin-like peptides have been studied intensively, but ...
Breugelmans, B +4 more
core +2 more sources
Innate immunity in the simplest animals – placozoans
BMC Genomics, 2019 Background Innate immunity provides the core recognition system in animals for preventing infection, but also plays an important role in managing the relationship between an animal host and its symbiont.
Kai Kamm, Bernd Schierwater, Rob DeSalle
doaj +1 more source
Early evolution of the LIM homeobox gene family
BMC Biology, 2010 Background LIM homeobox (Lhx) transcription factors are unique to the animal lineage and have patterning roles during embryonic development in flies, nematodes and vertebrates, with a conserved role in specifying neuronal identity.
Degnan Bernard M +6 more
doaj +1 more source