Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens. [PDF]
Sci Rep, 2016 AbstractThe identification of genes encoding a p53 family member and an Mdm2 ortholog in the ancient placozoan Trichoplax adhaerens advocates for the evolutionary conservation of a pivotal stress-response pathway observed in all higher eukaryotes. Here, we recapitulate several key functionalities ascribed to this known interacting protein pair by ...
Siau JW +7 more
europepmc +6 more sources
Cells containing aragonite crystals mediate responses to gravity in Trichoplax adhaerens (Placozoa), an animal lacking neurons and synapses. [PDF]
PLoS ONE, 2018 Trichoplax adhaerens has only six cell types. The function as well as the structure of crystal cells, the least numerous cell type, presented an enigma. Crystal cells are arrayed around the perimeter of the animal and each contains a birefringent crystal.
Tatiana D Mayorova +7 more
doaj +4 more sources
The ventral epithelium of Trichoplax adhaerens deploys in distinct patterns cells that secrete digestive enzymes, mucus or diverse neuropeptides [PDF]
Biology Open, 2019 The disk-shaped millimeter-sized marine animal, Trichoplax adhaerens, is notable because of its small number of cell types and primitive mode of feeding.
Tatiana D. Mayorova +4 more
doaj +4 more sources
Novel cell types, neurosecretory cells, and body plan of the early-diverging metazoan Trichoplax adhaerens. [PDF]
Curr Biol, 2014 Trichoplax adhaerens is the best-known member of the phylum Placozoa, one of the earliest-diverging metazoan phyla. It is a small disk-shaped animal that glides on surfaces in warm oceans to feed on algae. Prior anatomical studies of Trichoplax revealed that it has a simple three-layered organization with four somatic cell types.We reinvestigate the ...
Smith CL +8 more
europepmc +6 more sources
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens. [PDF]
EMBO Rep, 2011 The hypoxic response in humans is mediated by the hypoxia‐inducible transcription factor (HIF), for which prolyl hydroxylases (PHDs) act as oxygen‐sensing components. The evolutionary origins of the HIF system have been previously unclear. We demonstrate a functional HIF system in the simplest animal, Trichoplax adhaerens: HIF targets in T.
Loenarz C +6 more
europepmc +9 more sources
Studying Placozoa WBR in the Simplest Metazoan Animal, Trichoplax adhaerens.
Methods Mol Biol, 2022 AbstractPlacozoans are a promising model system to study fundamental regeneration processes in a morphologically and genetically very simple animal. We here provide a brief introduction to the enigmatic Placozoa and summarize the state of the art of animal handling and experimental manipulation possibilities.
Osigus HJ +7 more
europepmc +3 more sources
Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system. [PDF]
Proc Natl Acad Sci U S A, 2023 How collectives remain coordinated as they grow in size is a fundamental challenge affecting systems ranging from biofilms to governments. This challenge is particularly apparent in multicellular organisms, where coordination among a vast number of cells is vital for coherent animal behavior.
Davidescu MR +3 more
europepmc +6 more sources
Apicortin, a Putative Apicomplexan-Specific Protein, Is Present in Deep-Branching Opisthokonts [PDF]
BiologyApicortin, a tubulin/microtubule-binding protein, was first described in 2009 as a protein characteristic of apicomplexans; it was found to be present in all Apicomplexa genomes already sequenced.
Ferenc Orosz
doaj +2 more sources
Notizen: Spezifische Verbindungsstrukturen der Faserzellen von Trichoplax adhaerens F. E. Schulze/Special Connecting Structures between Fiber Cells of Trichoplax adhaerens F. E. Schulze [PDF]
Zeitschrift für Naturforschung C, 1974 Abstract In the primitive metazoan, Trichoplax adhaerens, the fiber cells are responsible for the change of shape. Electron microscopy reveals connections between protoplasmic strands of neighbouring cells marked by an osmiophilic disc-like structure. Possible functions are discussed.
F. Schulze +3 more
openalex +2 more sources
Trichoplax adhaerens F. E. Schulze (Placozoa): The Formation of Swarmers [PDF]
Zeitschrift für Naturforschung C, 1988 Abstract Flageilated swarmers representing an alternative mode of asexual reproduction are budded off as hollow spheres at the dorsal surface. They are covered by cells of the dorsal epithelium and the interior cavity is lined by ventral epithelium. Fiber cells are in the interspace.
Martin Thiemann, August Ruthmann
openalex +2 more sources