Results 21 to 30 of about 1,330 (177)
Trifluoromethylation of graphene
APL Materials, 2014 We demonstrate trifluoromethylation of graphene by copper-catalyzed free radical reaction. The covalent addition of CF3 to graphene, which changes the carbon atom hybridization from sp2 to sp3, and modifies graphene in a homogeneous and nondestructive ...
Lin Zhou +7 more
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Chimica Techno Acta, 2017 This review summarizes data on the reactions of chromones and activated alkenes with trimethyl(trifluoromethyl)silane (Ruppert’s reagent), which occures as a nucleophilic 1,4-trifluoromethylation with high regioselectivity and good yields.
V. Ya. Sosnovskikh, G.-V. Roshentaler
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Cu-Mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3
Beilstein Journal of Organic Chemistry, 2013 A Cu-mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3 was developed for the first time. This method offers a convenient and economical approach to various trifluoroethyl-containing compounds.
Xueliang Jiang, Feng-Ling Qing
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3-(4-Fluorophenyl)-1-(1-(4-fluorophenyl)-3,3,3-trifluoroprop-1-en-1-yl)-5-fluoro-1H-pyrazole
Molbank, 2023 In this work, the title compound was synthesized via the visible-light-induced radical denitrogenative trifluoromethylation of the corresponding vinyl azide followed by Cs2CO3-mediated defluorinative cyclization of the resultant azine.
Stanislav A. Paveliev +3 more
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Biocatalytic trifluoromethylation of unprotected phenols
Nature Communications, 2016 The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild ...
Robert C. Simon +5 more
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Molecules, 2017 We disclose herein the perfluoroalkylation of alkenes catalyzed by trifluoroethoxy-coated zinc phthalocyanine under irradiation of visible light. Perfluoroalkyl iodides were nicely incorporated into unsaturated substrates, including alkyne, to provide ...
Kohei Matsuzaki +3 more
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Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR
Molecules, 2010 A novel trifluoromethylated analogue of cADPR, 8-CF3-cIDPDE (5) was designed and synthesized via construction of N1,N9-disubstituted hypoxanthine, trifluoromethylation and intramolecular condensation.
Lihe Zhang +6 more
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Recent Advances in Trifluoromethylation Reactions with Electrophilic Trifluoromethylating Reagents
Chemistry – A European Journal, 2014 Abstract Electrophilic trifluoromethylation reactions have been the latest approach to achieve the fluoroalkylation of compounds with newly‐discovered reagents, such as the Togni’s (1‐trifluoromethyl‐1,2‐benziodoxol‐3‐(1 H)‐one), Umemoto’s (S‐(trifluoromethyl)dibenzothiophenium tetrafluoroborate), Yagupolskii’s (S‐
Barata Vallejo, Sebastian +2 more
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Divergent Access to Fluorinated Pharmacons From Ethyl Trifluoropyruvate. [PDF]
Adv Synth CatalFluoro(oxo) functional group diversification is traditionally accomplished through either specialized reagents or nucleophilic trifluoromethylation. Herein is disclosed the use of commercially available building blocks for the synthesis of trifluoromethyl(hydroxy) esters.
Nabi RN +4 more
europepmc +2 more sources
Molecules, 2022 Efficient visible-light-induced radical cascade trifluoromethylation/cyclization of inactivated alkenes with CF3Br, which is a nonhygroscopic, noncorrosive, cheap and industrially abundant chemical, was developed in this work, producing trifluoromethyl ...
Ransong Ma +7 more
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