Results 21 to 30 of about 1,340 (176)

High-Valent Ni^III and Ni^IV Species Relevant to C–C and C–Heteroatom Cross-Coupling Reactions: State of the Art

Molecules, 2020
Ni catalysis constitutes an active research arena with notable applications in diverse fields. By analogy with its parent element palladium, Ni catalysts provide an appealing entry to build molecular complexity via cross-coupling reactions.
Noel Nebra
doaj   +1 more source

Cu-Mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3

Beilstein Journal of Organic Chemistry, 2013
A Cu-mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3 was developed for the first time. This method offers a convenient and economical approach to various trifluoroethyl-containing compounds.
Xueliang Jiang, Feng-Ling Qing
doaj   +1 more source

Biocatalytic trifluoromethylation of unprotected phenols

Nature Communications, 2016
The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild ...
Robert C. Simon, Eduardo Busto, Nina Richter, Verena Resch, Kendall N. Houk, Wolfgang Kroutil   +5 more
doaj   +1 more source

Iron(II)-catalyzed trifluoromethylation of vinylcyclopropanes

上海师范大学学报. 自然科学版, 2016
An efficient iron(II)-catalyzed trifluoromethylation of vinylcyclopropanes was developed.A series of CF3-containing dihydronaphthalene derivatives were prepared with a moderate to high yield.This method offers several advantages in terms of its mild ...
LI Zongrui, DENG Qinghai
doaj   +1 more source

Recent Advances in Trifluoromethylation Reactions with Electrophilic Trifluoromethylating Reagents

Chemistry – A European Journal, 2014
Abstract Electrophilic trifluoromethylation reactions have been the latest approach to achieve the fluoroalkylation of compounds with newly‐discovered reagents, such as the Togni’s (1‐trifluoromethyl‐1,2‐benziodoxol‐3‐(1 H)‐one), Umemoto’s (S‐(trifluoromethyl)dibenzothiophenium tetrafluoroborate), Yagupolskii’s (S‐
Barata Vallejo, Sebastian, Lantaño, Beatriz, Postigo, Jose Alberto   +2 more
openaire   +3 more sources

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations

Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera, Francesco Basoccu, Andrea Porcheddu   +2 more
wiley   +2 more sources

CF3SO2X (X = Na, Cl) as reagents for trifluoromethylation, trifluoromethylsulfenyl-, -sulfinyl- and -sulfonylation. Part 1: Use of CF3SO2Na

Beilstein Journal of Organic Chemistry, 2017
Sodium trifluoromethanesulfinate, CF3SO2Na, and trifluoromethanesulfonyl chloride, CF3SO2Cl, are two popular reagents that are widely used for the direct trifluoromethylation of a large range of substrates.
Hélène Guyon, Hélène Chachignon, Dominique Cahard   +2 more
doaj   +1 more source

Regioselective 1,4-trifluoromethylation of α,β-unsaturated ketones via a S-(trifluoromethyl)diphenylsulfonium salts/copper system

Beilstein Journal of Organic Chemistry, 2013
Regioselective conjugate 1,4-trifluoromethylation of α,β-unsaturated ketones by the use of shelf-stable electrophilic trifluoromethylating reagents, S-(trifluoromethyl)diphenylsulfonium salts and copper under mild conditions is described. A wide range of
Satoshi Okusu, Yutaka Sugita, Etsuko Tokunaga, Norio Shibata   +3 more
doaj   +1 more source

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

Angewandte Chemie International Edition, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond, Esteban Suárez‐Picado, Lena von Sydow, Hanna Bruss, Laurent Knerr, Magnus Johansson, Anaïs Noisier, Lara R. Malins   +7 more
wiley   +1 more source

Trifluoromethylation of Secondary Nitroalkanes [PDF]

Organic Letters, 2017
Using a commercially available Umemoto's reagent, the metal-free trifluoromethylation of nitroalkanes is now possible. This method provides a general, high-yielding synthesis of α-(trifluoromethyl)nitroalkanes. The quaternary α-(trifluoromethyl)nitroalkanes obtained from this transformation can be elaborated to a variety of complex nitrogen-containing ...
Amber A. S. Gietter-Burch, Vijayarajan Devannah, Donald A. Watson   +2 more
openaire   +2 more sources