Sex Difference in Trigeminal Neuropathic Pain Response to Exercise: Role of Oxidative Stress
Aim. Orofacial chronic neuropathic pain commonly occurs following trigeminal nerve injuries. We investigated whether swimming exercise can reduce trigeminal neuropathic pain through improving antioxidant capacity. Materials and Methods.
Zahra Rostami +4 more
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The central nervous system (CNS) has, among all organ systems in the human body, the highest failure rate of traditional small-molecule drug development, ranging from 80–100% depending on the area of disease research.
Meenakshi Bose +3 more
doaj +1 more source
11th European Headache Federation Congress jointly with 31st Congress of the Italian Society for the Study of Headaches : Rome, Italy. 01-03 December 2017 [PDF]
. Aims of the study were explore the relationship between peripheral chromatic and central visual dysfunction evaluating also the presence of functional receptor impairment in patients with migraine, with and without aura examined ...
Brighina, F +5 more
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Intraoperative Neurophysiological Monitoring for Endoscopic Endonasal Approaches to the Skull Base: A Technical Guide. [PDF]
Intraoperative neurophysiological monitoring during endoscopic, endonasal approaches to the skull base is both feasible and safe. Numerous reports have recently emerged from the literature evaluating the efficacy of different neuromonitoring tests during
Doan, Adam T. +6 more
core +3 more sources
Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important [PDF]
Kynurenine pathway, the quantitatively main branch of tryptophan metabolism, has been long been considered a source of nicotinamide adenine dinucleotide, although several of its products, the so-called kynurenines, are endowed with the capacity to ...
CURTO, MARTINA +4 more
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Sensory disturbances of buccal and lingual nerve by muscle compression: a case report and review of the literature [PDF]
Introduction: Several studies on cadavers dissection have shown that collateral branches of the trigeminal nerve cross muscle bundles on their way, being a possible etiological factor of some nerve disturbances.
Alvira González, Joaquín +1 more
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Mechanosensory stimulation evokes acute concussion-like behavior by activating GIRKs coupled to muscarinic receptors in a simple vertebrate [PDF]
This work was supported by BBSRC (BB/L00111X).Most vertebrates show concussion responses when their heads are hit suddenly by heavy objects. Previous studies have focused on the direct physical injuries to the neural tissue caused by the concussive blow.
Li, Wen-Chang +2 more
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Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
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Multiple Morphometric Assessment of Microglial Cells in Deafferented Spinal Trigeminal Nucleus
Microglia (MG) are the first cells to react to the abnormal incoming signals that follow an injury of sensory nerves and play a critical role in the development and maintenance of neuropathic pain, a common sequel of nerve injuries.
Nuria García-Magro +6 more
doaj +1 more source
Neuronal circuitry for pain processing in the dorsal horn [PDF]
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception.
A Dhaka +159 more
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