Results 21 to 30 of about 273,980 (263)

Association of serum lipid levels, triglyceride–glucose index, systemic immune-inflammation index, and platelet-to-lymphocyte ratio with colorectal cancer: A retrospective study from China

Journal of International Medical Research
Objective This retrospective case–control study aimed to explore the correlations of blood lipid levels, triglyceride–glucose index, systemic immune-inflammation index, and platelet-to-lymphocyte ratio with colorectal cancer and evaluate their potential ...
Zhiwei Wang, Fanglai Zhu, Lu Dai
doaj   +1 more source

A Novel 3D Model Co‐Culturing Breast Cancer Cells in Direct Contact with Patient‐Derived Mature Adipocytes Demonstrates Cell‐Type Specific Alterations in Phenotype and Chemosensitivity

Advanced Healthcare Materials, EarlyView.
A novel 3D GelMA co‐culture model enabled sustained direct contact between patient‐derived mature adipocytes and breast cancer cells, revealing subtype‐specific interactions. MDA‐MB‐231 co‐culture caused adipocyte perilipin‐1 loss and reduced chemotherapy responsiveness, while MCF7 cells showed partial epithelial‐mesenchymal transition; both cell lines
Jessika A. Wise, Margaret J. Currie, Helen R. Morrin, Gretel S. Major, Tim B. F. Woodfield, Khoon S. Lim, Elisabeth Phillips   +6 more
wiley   +1 more source

Association between triglyceride-glucose and triglyceride-glucose related indices with all-cause mortality in depression participants: a cohort study from NHANES

Frontiers in Psychiatry
BackgroundWhile the triglyceride-glucose (TyG) index and related indices have been recognized as markers of insulin resistance and cardiometabolic disorders, few studies have examined their association with all-cause mortality in individuals with ...
Xinxing Wang, Chengya Feng, Bo Zhang, Guosong Jiang   +3 more
doaj   +1 more source

The role of triglyceride/glucose index in predicting coronary artery disease severity

Medicine Science, 2022
Triglyceride-glucose index is a novel marker for metabolic disorders and insulin resistance and is known to be in close association with the presence, prognosis, and severity of coronary artery disease.
Ahmet Rifki Cora, Ersin Celik
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Rapid determination of triglyceride and glucose levels in Drosophila melanogaster induced by high-sugar or high-fat diets based on near-infrared spectroscopy

Heliyon, 2023
Triglyceride and glucose levels are important indicators for determining metabolic syndrome, one of the leading public-health burdens worldwide. Drosophila melanogaster is an ideal model for investigating metabolic diseases because it has 70% homology to
Jiamin Huang, Pengwei Wang, Yu Wu, Li Zeng, Xiaoliang Ji, Xu Zhang, Mingjiang Wu, Haibin Tong, Yue Yang   +8 more
doaj   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source

Relationship between the triglyceride glucose index and time in range: A cross-sectional study based on patients with type 2 diabetes mellitus

Journal of International Medical Research
Objective The objective of this study was to investigate the relationship between the triglyceride glucose index and time in range in patients with type 2 diabetes mellitus.
Hongbo Shang, Xiaoli Qin, Wenxian Li, Yanrong Xu, Weixuan Wang   +4 more
doaj   +1 more source

Triglyceride glucose index can predict the risk of contrast-induced nephropathy undergoing percutaneous coronary intervention: a systematic review and meta-analysis

Journal of the Pakistan Medical Association
Objective: To investigate the association between triglyceride glucose index and contrast-induced nephropathy in patients after percutaneous coronary intervention.
Shuxiong Ge, Jinlin Yan, Hui Wang
doaj   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source