Results 31 to 40 of about 273,980 (263)

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Association between various insulin resistance indices and cardiovascular disease in middle-aged and elderly individuals: evidence from two prospectives nationwide cohort surveys

Frontiers in Endocrinology
BackgroundThe estimated glucose disposal rate (eGDR), triglyceride glucose (TyG), triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, and metabolic score for insulin resistance (METS-IR) are dependent indicators of insulin resistance ...
Yan Li, Huijuan Li, Xiaoyu Chen, Xiaoyu Chen, Xueyan Liang   +4 more
doaj   +1 more source

Triglyceride and glucose (TyG) index as a predictor of incident hypertension: a 9-year longitudinal population-based study

Lipids in Health and Disease, 2017
Background Hypertension and the triglyceride and glucose index both have been associated with insulin resistance; however, the longitudinal association remains unclear.
Rongjiong Zheng, Yushan Mao
doaj   +1 more source

Pengaruh Substitusi Tepung Ikan dengan Tepung Keong Mas (Pomacea Canaliculata L.) di dalam ransum basal terhadap Plasma Metabolit Ayam Broiler Fase Starter

Jurnal Agripet, 2020
ABSTRAK. Keong mas (Pomacea canaliculata L.) merupakan bahan pakan alternatif bagi unggas yang memiliki kandungan protein tinggi yang hampir sama dengan tepung ikan. Penelitian ini bertujuan untuk mengetahui pengaruh penggantian tepung ikan dengan tepung
Alpian Arbi Harahap, Edi Erwan, Dewi Febrina   +2 more
doaj   +1 more source

The triglyceride glucose related index is an indicator of Sarcopenia

Scientific Reports
The triglyceride glucose (TyG) related index, a metric used to evaluate assessing insulin resistance (IR), has received limited attention in its association with sarcopenia. Our study aims to explore the predictive potential of the TyG index for sarcopenia.
Zihao Zhang, Xin Chen, Na Jiang
openaire   +3 more sources

Fructose impairs glucose-induced hepatic triglyceride synthesis [PDF]

Lipids in Health and Disease, 2011
AbstractObesity, type 2 diabetes and hyperlipidemia frequently coexist and are associated with significantly increased morbidity and mortality. Consumption of refined carbohydrate and particularly fructose has increased significantly in recent years and has paralled the increased incidence of obesity and diabetes.
Huang, Danshan, Dhawan, Tania, Young, Stephen, Yong, William H, Boros, Laszlo G, Heaney, Anthony P   +5 more
openaire   +5 more sources

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Development and validation of machine learning models for MASLD: based on multiple potential screening indicators

Frontiers in Endocrinology
BackgroundMultifaceted factors play a crucial role in the prevention and treatment of metabolic dysfunction-associated steatotic liver disease (MASLD).
Hao Chen, Jingjing Zhang, Xueqin Chen, Ling Luo, Wenjiao Dong, Yongjie Wang, Jiyu Zhou, Canjin Chen, Wenhao Wang, Wenbin Zhang, Zhiyi Zhang, Yongguang Cai, Danli Kong, Yuanlin Ding   +13 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Association of triglyceride/high density lipoprotein cholesterol， triglyceride-glucose index and dysfunction of arteriovenous fistula in maintenance hemodialysis patients

Linchuang shenzangbing zazhi
ObjectiveTo explore the correlation between triglyceride/high density lipoprotein cholesterol， triglyceride-glucose index and arteriovenous fistula dysfunction in maintenance hemodialysis （MHD） patients.MethodsFrom January 2018 to October 2022， the ...
He Lei, Chen Xiao-qin, Cao Jing-yuan, Zhao Xiao-qian, Zou Chun-bo   +4 more
doaj   +3 more sources